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Azafenidin
go.drugbank.com/drugs/DB19031InvestigationalAzafenidin is under investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")).
Synonyms: 2-(2,4-dichloro-5-(2-propynyloxy)phenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one, 2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-oneTPX-4589
go.drugbank.com/drugs/DB18604InvestigationalTPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Synonyms: Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAESTRO-001
go.drugbank.com/drugs/DB17224InvestigationalSynonyms: STRO-001, a site-specific anti-CD74 antibody-drug conjugate, antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable maytansinoid linker warheads(6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one
go.drugbank.com/drugs/DB07148ExperimentalSynonyms: (6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-oneAnti-CD7 CAR T-cell therapy
go.drugbank.com/drugs/DB18128ExperimentalSynonyms: A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7, Anti-CD7 CAR T-cell therapyKUR-113
go.drugbank.com/drugs/DB18413InvestigationalKUR-113 is an investigational fibrin-based agent containing an N-terminally modified parathyroid hormone fragment. It is being investigated as a bioactive bone graft substitute.
Synonyms: Fibrin-based agent containing a N-terminally modified parathyroid hormone fragment TGplPTH1-342-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
go.drugbank.com/drugs/DB07574ExperimentalSynonyms: 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDEAclerastide
go.drugbank.com/drugs/DB12631InvestigationalAclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.
Synonyms: NorLeu3-A(1-7), NorLeu3-Angiotensin(1-7) [NorLeu3-A(1-7)]JQ1
go.drugbank.com/drugs/DB17021ExperimentalFirst-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]
Synonyms: (s)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate, Tert-butyl 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetateARGX-119
go.drugbank.com/drugs/DB18133InvestigationalARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Synonyms: a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and activates MuSK