Aclerastide

DB12631InvestigationalSmall molecule

Aclerastide has been investigated for the treatment of Diabetic Foot, Diabetic Foot Ulcers, and Foot Ulcer, Diabetic.

Chemical structure of Aclerastide
Formula / weight
C42H64N12O11 · 913.047 g/mol (avg)
Also known as
1-7-ANGIOTENSIN II, 3-L-NORLEUCINE-5-L-ISOLEUCINE · ASP-ARG-NLE-TYR-ILE-HIS-PRO · NorLeu3-A(1-7) · NORLEU3-ANGIOTENSIN(1-7) · NorLeu3-Angiotensin(1-7) [NorLeu3-A(1-7)]
Code names
DSC-127 · USB-001 · USB 005

Resolves to

Compound
UNIIYYD6UT8T47CAS227803-63-6PubChem9811551
Structure
InChIKeyRUBMHAHMIJSMHA-LBWFYSSPSA-NSMILES[H]N([C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N1CCC[C@H]1C(O)=O)C(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O
Targets
P04201MAS1

What you can answer from here — as of January 29, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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3Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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