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Displaying results 5291 - 5300 of 10000 in total
  1. Drug

    Goserelin

    go.drugbank.com/drugs/DB00014
    ApprovedInvestigational

    Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. … In women, goserelin decreases the production of the hormone estradiol (which may stimulate the growth of cancer cells) to levels similar to a postmenopausal state.

    Products: ZOLADEX ® LA 10.8 MG, ZOLADEX ® 3.6MG
  2. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Still docusate is available in over-the-counter products as a common laxative. … Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation[A32201].

    Mixtures: Laxatif De Sene Et Docusate De Sodium, Sennosides 8.6 Mg and Docusate Sodium 50 Mg TabletsProducts: Sirop Docusate De Sodium U.S.P. 4mg/ml, H E B Stool Softener laxative
  3. Drug

    Ramucirumab

    go.drugbank.com/drugs/DB05578
    ApprovedInvestigational

    By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, … In contrast to other agents directed against VEGFR-2, ramucirumab binds a specific epitope on the extracellular domain of VEGFR-2, thereby blocking all VEGF ligands from binding to it.

    Categories: Vascular Endothelial Growth Factor Receptor 2 AntagonistProducts: CYRAMZA 500 MG/50 ML İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇEREN FLAKON, 1 ADET, CYRAMZA 100MG/10 ML INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇEREN FLAKON, 2 ADET
  4. Drug

    Ritodrine

    go.drugbank.com/drugs/DB00867
    ApprovedWithdrawn

    Adrenergic beta-agonist used to control premature labor.

    Synonyms: p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcoholCategories: Adrenergic beta-2 Receptor Agonists
  5. Drug

    Fomepizole

    go.drugbank.com/drugs/DB01213
    ApprovedVet approved

    Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.

    Synonyms: 4-methylpyrazol, 4-methylpyrazoleCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Inhibitors
  6. Drug

    Dezamizumab

    go.drugbank.com/drugs/DB15153
    Investigational

    Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS APCS (AMYLOID P COMPONENT SERUM, SERUM AMYLOID P COMPONENT, SAP, PENTRAXIN-2, PTX2)), HUMANIZED MONOCLONAL ANTIBODY, recombinant monoclonal antibody to human serum amyloid P component
  7. Drug

    Fluocortolone

    go.drugbank.com/drugs/DB08971
    ApprovedWithdrawn

    Fluocortolone is a glucocorticoid with anti-inflammatory activity used topically for various skin disorders.

    Mixtures: เชริพร็อค(R) เอ็น, SCHERIPROCT N CREAMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  8. Drug

    Taniraleucel

    go.drugbank.com/drugs/DB18311
    Investigational

    Synonyms: The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell
  9. Drug

    Fosfomycin

    go.drugbank.com/drugs/DB00828
    ApprovedInvestigational

    [A230348] Due to its ease of administration as a single 3-gram oral dose and desirable safety profile, fosfomycin has largely become a first-line therapeutic option for the treatment of uncomplicated … [A230348] In terms of chemical structure, fosfomycin is a phosphoenolpyruvate analog and contains a phosphonic group and an epoxide ring.

    Synonyms: L-cis-1,2-epoxypropylphosphonic acid, (2R-cis)-(3-Methyloxiranyl)phosphonic acidProducts: SOLUFOS® 500 MG, FOSFOCIL GU
  10. Drug

    Vericiguat

    go.drugbank.com/drugs/DB15456
    ApprovedInvestigational

    [A227458,A227488] Cyclic GMP acts as a second messenger, activating a number of downstream signaling cascades that elicit a broad variety of effects, and these diverse cellular effects have implicated … deficiencies in its production (primarily due to insufficient NO bioavailability) in the pathogenesis of various cardiovascular diseases.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: VERQUVO 5 MG FİLM KAPLI TABLET , 28 ADET, VERQUVO 5 MG FİLM KAPLI TABLET , 14 ADET