Fomepizole

DB01213ApprovedVet approvedSmall moleculeAntidotes

Fomepizole is an inhibitor of alcohol dehydrogenase used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning.

Chemical structure of Fomepizole
Mechanism
Curator reviewed
Primary indication
Antizol is indicated as an antidote for ethylene glycol (such as antifreeze) or methanol poisoning, or for use in suspected ethylene glycol or methanol ingestion, either alone or in combination with hemodialysisCurator reviewed · 2 structured indications
Formula / weight
C4H6N2 · 82.1038 g/mol (avg)
First approval
Canada, 2014 · United States, 2007
Also known as
4-methylpyrazol · 4-methylpyrazole
Brand names
  • Antizol

Resolves to

Compound
UNII83LCM6L2BYCAS7554-65-6ChEMBLCHEMBL1308ChEBI5141PubChem3406KEGGD00707
Clinical / RWD
RxNorm15226ATCV03AB34PharmGKBPA449697
Structure
InChIKeyRIKMMFOAQPJVMX-UHFFFAOYSA-NSMILESCC1=CNN=C1
Targets
P07327ADH1AP00325ADH1BP00326ADH1CP04040CAT

What you can answer from here — as of September 23, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
783Drug interactionsStructured to mechanism, not free text
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5Clinical trialsPhase, status and sponsor resolved per trial
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2Structured indicationsCondition, population, route and combination as fields, not prose
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1ContraindicationEach with its own population and attribute set
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15Marketed productsAcross 3 countries and 15 labellers
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1ATC codeIncluding every combination product, plus 17 drug categories
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23+ReferencesStructured and connected to the statements they support
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