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Ohmefentanyl
go.drugbank.com/drugs/DB01570ExperimentalIllicitOhmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently named F9201–F9208.
3-Methylfentanyl
go.drugbank.com/drugs/DB01571ExperimentalIllicit3-Methylfentanyl is an opioid analgesic and is an analog of the potent opioid, fentanyl. 3-Methylfentanyl is one of the most powerful opioid drugs sold illegally and is estimated to be between 400-6000 times more potent than morphine in ...
Pomaglumetad methionil
go.drugbank.com/drugs/DB05096InvestigationalLY2140023 is an oral "prodrug," meaning it is devoid of intrinsic biological activity and, once administered, is metabolized to provide the active mGlu2/3 receptor agonist called LY404039.
Arbaclofen Placarbil
go.drugbank.com/drugs/DB08892InvestigationalIt was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties.
TM5614
go.drugbank.com/drugs/DB16516InvestigationalTM5614 inhibition of PAI-1, specifically, downregulates PCSK9 at the transcriptional level[A228793].
Daclizumab
go.drugbank.com/drugs/DB00111ApprovedInvestigationalWithdrawnThe human sequences were derived from the constant domains of human IgG1 and the variable framework regions of the Eu myeloma antibody.
Vilanterol
go.drugbank.com/drugs/DB09082ApprovedInvestigational[A259966] Additionally, vilanterol demonstrated a significantly longer duration of action than salmeterol, with the bronchodilator effect still apparent at 22h.
IMM101
go.drugbank.com/drugs/DB15851ExperimentalIt has shown to be safe and well tolerated to complement conventional cancer therapy for patients with melanoma and pancreatic ductal adenocarcinoma [PMID: 21930686; PMID: 30107850; PMID: 27599039].
Surotomycin
go.drugbank.com/drugs/DB12076InvestigationalIt is a benzenebutanoic acid derivative patented by Cubist Pharmaceuticals, Inc. as antibacterial agents for the treatment of Gram-positive infections.