Search

Displaying results 5321 - 5330 of 10000 in total
  1. Drug

    Nicotinyl alcohol

    go.drugbank.com/drugs/DB04145
    Experimental

    It is used in vasospasm and threatened gangrene. [PubChem]

  2. Drug

    Alrizomadlin

    go.drugbank.com/drugs/DB17549
    Investigational

    It is being investigated in cancers.[A257281,A257286]

    Synonyms: (3'r,4's,5'r)-4-((6-chloro-2-oxo-1,2-dihydro-spiro(indole-3,3'-pyrrolidin)e-4'-(3-chloro-2-fluoro -phenyl)-1'-ethyl-spiro(cyclohexane-1,2'-pyrrolidine)-5'-carbonyl)-amino)-bicyclo(2.2.2)octane-1-carboxylic
  3. Drug

    Diazepinomicin

    go.drugbank.com/drugs/DB12420
    Investigational

    It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well known chemotherapeutics, doxorubicin and mitomycin C. … in vitro models.

    Synonyms: 4,6,8-trihydroxy-10-(3,7,11-trimethyldodeca-2,6,10-trienyl)-5,10-dihydrodibenzo(b,e)(1,4)diazepin-11-one
  4. Drug

    VTX-801

    go.drugbank.com/drugs/DB17646
    Investigational

    It is being investigated in Wilson Disease.[L45924] … VTX-801 is a replication-deficient recombinant adeno-associated viral vector (rAAV) consisting of an AAV liver tropic capsid containing a single-stranded DNA genome carrying a shortened version of the

  5. Drug

    Coagulin-B

    go.drugbank.com/drugs/DB17703
    Experimental

    [A259038, A259043] It was previously investigated for the treatment of hemophilia; however, the manufacturing company discontinued the Phase I trial in 2004, halting its further development and investigation … Coagulin-B is an adeno-associated viral vector expressing human blood-coagulation Factor IX.

  6. Drug

    OSI-930

    go.drugbank.com/drugs/DB05913
    Investigational

    In preclinical studies, OSI-930 shows broad efficacy in tumor models representative of small cell lung cancer, glioblastoma, colorectal, renal, head and neck, non-small cell lung cancer and gastric cancers … OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors.

  7. Drug

    VIR201

    go.drugbank.com/drugs/DB05110
    Experimental

    is an experimental therapeutic vaccine currently in clinical trial. The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.

  8. Drug

    Atigotatug

    go.drugbank.com/drugs/DB14831
    Investigational

    It is under investigation in clinical trial NCT02815592 (Trial of BMS-986012 in Combination With Platinum and Etoposide).

    Synonyms: anti-[Fucosyl-GM1 (fucosylated monosialoganglioside 1)], Homo sapiens monoclonal antibody; H-gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV3-48*02 (90.7%) -(IGHD) -IGHJ3*01 (92.3%) M123>T
  9. Drug

    ISO-1 F-18

    go.drugbank.com/drugs/DB14900
    Investigational

    ISO-1 F-18 is under investigation in clinical trial NCT00968656 (Assessment of Cellular Proliferation in Tumors by Positron Emission Tomography (PET) Using [18F]ISO-1).

  10. Drug

    ORM-13070 C-11

    go.drugbank.com/drugs/DB15324
    Investigational

    ORM-13070 C-11 is under investigation in clinical trial NCT00735774 (Suitability of 11C-ORM-13070 as a PET Tracer).