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Displaying results 5341 - 5350 of 10000 in total
  1. Drug

    Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine

    go.drugbank.com/drugs/DB15813
    Investigational

    Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. … Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these engineered minigenes to express viral proteins, modify artificial antigen presenting cells (aAPC), and activate T-cells

  2. Drug

    COVID19 s-vax loaded autologous dendritic cell vaccine

    go.drugbank.com/drugs/DB15814
    Experimental

    The rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can induce a more prolific immune response. … These cells are then loaded with antigens produced by a virus or tumor cell and administered as a vaccine.

  3. Drug

    Fluocortolone caproate

    go.drugbank.com/drugs/DB15821
    Investigational

    Mixtures: ULTRALAN KREM, 10 G, ULTRALAN KREM, 20 G
  4. Drug

    Pralsetinib

    go.drugbank.com/drugs/DB15822
    ApprovedInvestigational

    [A202049, A202055, L15986] Although a phase 1/2 trial of pralsetinib termed ARROW (NCT03037385) is still ongoing, pralsetinib was granted accelerated FDA approval on September 4, 2020, for the treatment … It is currently marketed under the brand name GAVRETO™ by Blueprint Medicines.[L15986]

    Categories: MATE 1 Inhibitors, MATE 2 Inhibitors
  5. Drug

    Lecithin

    go.drugbank.com/drugs/DB15834
    Investigational

    A complex mixture of phospholipids, glycolipids, triglycerides, phosphatidylcholines, phosphatidylethanolamines, and phosphatidylinositols.

    Mixtures: aspen nutrition Omega 3-6-9, Live-wellâ„¢ MEMOSENTIALâ„¢ CapsuleCategories: P-glycoprotein substrates, Compounds used in a research, industrial, or household setting
  6. Drug

    Cedar leaf oil

    go.drugbank.com/drugs/DB15836
    Investigational

    Mixtures: KATALJÄ°N BUHARLAÅžAN MERHEM, 40 G, KATALJÄ°N BUHARLAÅžAN MERHEM, 12,5 G
  7. Drug

    Sodium metabisulfite

    go.drugbank.com/drugs/DB15842
    Investigational

    Mixtures: NEOFLEKS IZOPLEN-M % 5 DEKSTROZLU DENGELI ELEKTROLIT IÇEREN INFÜZYON IÇIN ÇÖZELTI 1000 ML SETLI, NEOFLEKS IZOPLEN-M % 5 DEKSTROZLU DENGELI ELEKTROLIT IÇEREN INFÜZYON IÇIN ÇÖZELTI 1000 ML SETSIZ
  8. Drug

    Zorecimeran

    go.drugbank.com/drugs/DB15843
    Investigational

    As of June 2020, the company received regulatory approval from German and Belgian Authorities to commence Phase 1 clinical trials of this vaccine (NCT04449276). … The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body.

  9. Drug

    COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection

    go.drugbank.com/drugs/DB15845
    Experimental

    As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ … The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.

    Synonyms: AP-TP-V
  10. Drug

    IMM101

    go.drugbank.com/drugs/DB15851
    Experimental

    IMM-101 is a heat-inactivated immune-activating mycobacterial product. … As of July 2020, researchers from the Ottawa Hospital and Queen’s University, in partnership with the Canadian Cancer Society-funded Canadian Cancer Trials Group (CCTG), are conducting a trial in over