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Displaying results 5351 - 5360 of 10000 in total
  1. Drug

    Tyrosinase

    go.drugbank.com/drugs/DB16626
    Investigational

    [A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum. … [A231829, A231834, A231839] Within mammals, tyrosinase is found specifically in melanocytes in a glycosylated form and plays a critical role in regulating the process of melanin biosynthesis (also known

  2. Drug

    UCB7362

    go.drugbank.com/drugs/DB17096
    Experimental

    [A254232] UCB7362 is estimated to achieve a significant reduction in asexual blood-stage parasites. … UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria.

  3. Drug

    7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE

    go.drugbank.com/drugs/DB07512
    Experimental

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  4. Drug

    Methysergide

    go.drugbank.com/drugs/DB00247
    ApprovedWithdrawn

    An ergot derivative that is a congener of lysergic acid diethylamide.

    Categories: Heterocyclic Compounds with 4 or More Rings
  5. Drug

    Ibuzatrelvir

    go.drugbank.com/drugs/DB19451
    Investigational

    Are at Risk for Severe Disease). … Ibuzatrelvir is under investigation in clinical trial NCT06679140 (A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized but

  6. Drug

    Theralizumab

    go.drugbank.com/drugs/DB15717
    Investigational

    Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer.

  7. Drug

    Reparixin

    go.drugbank.com/drugs/DB12614
    Investigational

    Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type

  8. Drug

    Palucorcel

    go.drugbank.com/drugs/DB17955
    Investigational

    Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.

  9. Drug

    Olcegepant

    go.drugbank.com/drugs/DB04869
    Investigational

    Boehringer Ingelheim Pharmaceuticals’ olcegepant (BIBN 4096) is a selective Calcitonin Gene-Related Peptide (CGRP) antagonist, a new class of drugs in development for the treatment of acute migraine attacks … Olcegepant is undergoing phase II trials in Europe and the US, with preliminary results suggesting that CGRP antagonists may represent a potential new approach to the treatment of migraine.

  10. Drug

    ABBV-514

    go.drugbank.com/drugs/DB17586
    Investigational

    ABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]