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Camidanlumab tesirine
go.drugbank.com/drugs/DB16411InvestigationalCamidanlumab tesirine is under investigation in clinical trial NCT04639024 (ADCT-301 in Patients With R/R AML, MDS, or MDS/MPN).
HMI-103
go.drugbank.com/drugs/DB17684InvestigationalHMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Col-Treg
go.drugbank.com/drugs/DB18451ExperimentalCol-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.[A261635]
HRS-1167
go.drugbank.com/drugs/DB18703InvestigationalHRS-1167 is under investigation in clinical trial NCT05473624 (Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors).
RCT1100
go.drugbank.com/drugs/DB18830InvestigationalRCT1100 is an investigational mRNA-based therapeutic that aims to treat primary ciliary dyskinesia caused by pathogenic mutations in DNAI1.[L50788]
Yeast beta-D-glucan
go.drugbank.com/drugs/DB19271InvestigationalYeast beta-D-glucan is under investigation in clinical trial NCT00632008 (Soluble Beta-glucan (SBG) as Treatment for Diabetic Foot Ulcers).
GSK-239512
go.drugbank.com/drugs/DB15120InvestigationalGSK-239512 is under investigation in clinical trial NCT00474513 (An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.).
Fosmanogepix
go.drugbank.com/drugs/DB15183InvestigationalFosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
Tiazofurine
go.drugbank.com/drugs/DB13243ExperimentalTiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase [A174991].
1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine
go.drugbank.com/drugs/DB01562ExperimentalIllicit1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. It is sold as a "synthetic heroin."