Search
Interferon Kappa
go.drugbank.com/drugs/DB15749Experimentala 27-amino acid signal peptide conserved in type I interferons. … This gene encoding for this interferon is expressed in human epidermal keratinocytes.
Synonyms: IFN‐κNorelgestromin
go.drugbank.com/drugs/DB06713ApprovedInvestigationalIt is administered transdermally in combination with the estrogen [ethinyl estradiol], delivering both hormones systemically over a 7-day wear period. … Norelgestromin was first approved in the United States in 2001 as the progestin in a norelgestromin and ethinyl estradiol transdermal contraceptive system.[L63816]
Mixtures: EVRA®, Evra -(6/0.75)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesR1626
go.drugbank.com/drugs/DB05060ExperimentalIt achieves significant reductions in viral load in chronic hepatitis C patients infected with the difficult to treat genotype 1 virus. R1626 is very effective in inhibiting viral replication … R1626 is one of a new class of hepatitis C therapies called polymerase inhibitors.
TA-NIC
go.drugbank.com/drugs/DB05445InvestigationalTA-NIC is a novel and proprietary vaccine in development as an aid to quitting smoking in motivated patients. … It is designed to raise anti-nicotine antibodies which bind to nicotine molecules in the patient's blood stream, reducing the rate and quantity of nicotine entry into the brain, to reduce the addictive
CK0802
go.drugbank.com/drugs/DB15866InvestigationalCK0802 is an off-the-shelf product composed of allogeneic umbilical cord blood derived regulatory T-cells (T-Reg cells), which can be used intravenously and without HLA matching. … [L16358] On the surface of these T-Reg cells, T-cell lung homing markers are expressed.
Synonyms: Allogeneic Umbilical Cord Blood Derived Regulatory T-CellsBenmoxin
go.drugbank.com/drugs/DB09246ApprovedWithdrawnBenmoxin is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class. It was first synthesized in 1967 and rapidly used in Europe as an antidepressant. … However, this agent is no longer marketed.
Ranpirnase
go.drugbank.com/drugs/DB04950InvestigationalRanpirnase is a ribonuclease enzyme found in <i>Rana pipiens</i> oocytes. It is being studied in the treatment of cancer. It is manufactured by Alfacell Corporation. … It is the first ribonuclease to enter cancer clinical trials.
Tezosentan
go.drugbank.com/drugs/DB06558InvestigationalTezosentan is an intravenous endothelin receptor A/B antagonist. … Tezosentan was initially developed for vasodilation in patients with acute heart failure but studies have shown that it does not assist in the treatment of dyspnea or prevent cardiovascular events.
Categories: Heterocyclic Compounds, 1-RingPhenindamine
go.drugbank.com/drugs/DB01619ApprovedSymptoms of a phenindamine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and … Phenindamine is an antihistamine. Phenindamine blocks the effects of the naturally occurring chemical histamine in your body.
Categories: Heterocyclic Compounds, 1-RingBudiodarone
go.drugbank.com/drugs/DB05519InvestigationalBudiodarone (ATI-2042) is an antiarrhythmic related to amiodarone that is currently being studied in clinical trials.
Categories: Heterocyclic Compounds, 2-Ring