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Osemozotan
go.drugbank.com/drugs/DB05339ExperimentalMN-305 is a novel, potent and highly selective serotonin 5-HT1A receptor agonist under development by MediciNova for the treatment of anxiety disorders beginning with Generalized Anxiety Disorder (GAD)
Nomacopan
go.drugbank.com/drugs/DB14991InvestigationalNomacopan is under investigation in clinical trial NCT03427060 (Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms).
Sifalimumab
go.drugbank.com/drugs/DB12773InvestigationalSifalimumab may suppress the abnormal immune activity associated with lupus by binding to multiple interferon-alpha subtypes seen in the serum of lupus patients.
Brolamfetamine
go.drugbank.com/drugs/DB01484ExperimentalIllicitCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeGT 389-255
go.drugbank.com/drugs/DB05894ExperimentalIt is expected to block fat absorption with fewer side effects than currently marketed lipase inhibitors.
DYNE-251
go.drugbank.com/drugs/DB18130InvestigationalDYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1). … It is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping.
Alphaprodine
go.drugbank.com/drugs/DB13160ExperimentalIllicitCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCedirogant
go.drugbank.com/drugs/DB18951InvestigationalCedirogant is under investigation in clinical trial NCT05044234 (A Study to Assess Adverse Events and Disease Activity With Cedirogant (ABBV-157) in Adult Participants With Moderate to Severe Psoriasis
Atuliflapon
go.drugbank.com/drugs/DB19029InvestigationalAtuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-severe Uncontrolled Asthma).
Synonyms: (1r,2r)-2-(4-(3-methyl-1h-pyrazol-5-yl)benzoyl)-n-(4-oxo-6,7-dihydro-5h-pyrazolo(1,5-a)pyrazine-3-yl)cyclohexanecarboxamide, Cyclohexanecarboxamide, 2-(4-(5-methyl-1h-pyrazol-3-yl)benzoyl)-n-(4,5,6,7-tetrahydro-4-oxopyrazolo(1,5-a)pyrazin-3-yl)-, (1r,2r)-