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Displaying results 531 - 540 of 4584 in total
  1. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes ...

    Mixtures: Benadryl Bug Bite Relief, Children's Benadryl Bug Bite ReliefProducts: Allergy Relief, 24-7 Lift by 7-Eleven
  2. Drug

    Buprenorphine

    go.drugbank.com/drugs/DB00921
    ApprovedIllicitInvestigationalVet approved

    [A186292] This means that buprenorphine preferentially binds the opioid receptor and displaces lower affinity opioids without activating the receptor to a comparable degree. … Combination with naloxone is intended to reduce the abuse potential of Suboxone, as naloxone is poorly absorbed by the oral route (and has no effect when taken orally), but would reverse the opioid agonist

  3. Drug

    LX1031

    go.drugbank.com/drugs/DB05199
    Investigational

    LX1031 is designed to act locally in the gastrointestinal tract by reducing the serotonin available for receptor activation, without affecting serotonin levels in the brain or its central nervous system … LX1031 was generated by Lexicon medicinal chemists, and its target was internally identified as a key control point for the regulation of peripheral serotonin levels.

  4. Drug

    Nifurtimox

    go.drugbank.com/drugs/DB11820
    ApprovedInvestigational

    [L15366] The CDC estimates that approximately 8 million people in Central America, South America, and Mexico are infected with T. cruzi, without symptoms. … [L15361] A convenient feature of Bayer's formulation is the ability to divide the scored tablets manually without the need for pill-cutting devices.[L15361]

  5. Drug

    Zinc sulfate

    go.drugbank.com/drugs/DB09322
    ApprovedInvestigational

    Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic heal...

    Mixtures: Clear Eyes Acr By Murine
  6. Drug

    Atorvastatin

    go.drugbank.com/drugs/DB01076
    ApprovedInvestigational

    statin use leads to a 20%-22% relative reduction in the number of major cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without … [A181397, A181403] Atorvastatin was first synthesized in 1985 by Dr. Bruce Roth and approved by the FDA in 1996.

  7. Drug

    Codeine

    go.drugbank.com/drugs/DB00318
    ApprovedIllicitInvestigational

    Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory

  8. Drug

    Chromium

    go.drugbank.com/drugs/DB11136
    ApprovedInvestigational

    Humans can be exposed to chromium via ingestion, inhalation, and dermal or ocular exposure [L1983].

    Mixtures: Vita Balance 2000, Super Vita-vim With Beta-carotene - Tab
  9. Drug

    Imdevimab

    go.drugbank.com/drugs/DB15940
    ApprovedInvestigational

    [L23524] In November 2021, the same indication was approved by the EMA. … [A221495] On November 21, 2020, the FDA authorized emergency approval of REGN-COV2 to treat mild to moderate COVID-19 in patients aged 12 years and older.

  10. Drug

    Antithymocyte immunoglobulin (rabbit)

    go.drugbank.com/drugs/DB00098
    ApprovedInvestigational

    The most common mode of action of Thymoglobulin is via selective depletion of T-cells.