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Clofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalClofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.
Categories: OCT2 Substrates with a Narrow Therapeutic Index, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexSynonyms: Cl-F-Ara-A, (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one
go.drugbank.com/drugs/DB08703ExperimentalSynonyms: 12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one(1R,2R,3R,4S,5R)-4-(Benzylamino)-5-(methylthio)cyclopentane-1,2,3-triol
go.drugbank.com/drugs/DB06984ExperimentalSynonyms: Benzylation of mannostatin A, 1b, (1R,2R,3R,4S,5R)-4-(Benzylamino)-5-(methylthio)cyclopentane-1,2,3-triolN-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide
go.drugbank.com/drugs/DB07879ExperimentalSynonyms: N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamideN-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine
go.drugbank.com/drugs/DB08057ExperimentalSynonyms: N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amineFlubentylosin
go.drugbank.com/drugs/DB17769InvestigationalSynonyms: 4''-(p-fluorobenzyl)tylosin a, 4b-o-((4-fluorophenyl)methyl)tylosinRubella virus vaccine
go.drugbank.com/drugs/DB10317ApprovedInvestigationalIt is prepared from RA 27/3 strain of live attenuated rubella virus. Rubella is a common childhood disease, caused by rubella virus (togavirus). … Rubella virus vaccine is a live attenuated virus vaccine for active immunization against rubella (German measles) that is subcutaneously administered.
Synonyms: Rubella virus live antigen, A, Rubivirus rubella virus Wistar RA 27/3 wholeMixtures: SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 dose, <p>SII MEASLES,MUMPS & RUBELLA VACCINE LIVE ATTENUATED (FREEZE-DRIED) SINGLE DOSE</p>Tovinontrine
go.drugbank.com/drugs/DB16193InvestigationalTovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease). … Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor.
Synonyms: 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A)PYRAZIN-8(7H)-ONE, 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin-8-oneMeasles virus vaccine live attenuated
go.drugbank.com/drugs/DB10315ApprovedInvestigationalMeasles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease. … The vaccine is prepared from the attenuated line of measles virus, derived from Enders' attenuated Edmonston strain and propagated in chick embryo cell culture.
Mixtures: SII Measles and Rubella Virus Vaccine live.Attenuated(Freeze-Dried) 1 dose, <p>SII MEASLES,MUMPS & RUBELLA VACCINE LIVE ATTENUATED (FREEZE-DRIED) SINGLE DOSE</p>Synonyms: Measles virus live antigen, ACyclo(prolylglycyl)
go.drugbank.com/drugs/DB04541InvestigationalNA-831 (Traneurocin), is under investigation in two clinical trials: NCT03538522 (completed, for mild cognitive impairment and Alzheimer’s disease) and NCT04452565 (unknown status, combination therapy
Synonyms: (S)-Hexahydropyrrolo(1,2-a)pyrazine-1,4-dione-4-17O, Cyclo(pro-O-gly)