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Warfarin
go.drugbank.com/drugs/DB00682ApprovedInvestigationalAlthough originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. … Warfarin does not actually affect blood viscosity, rather, it inhibits vitamin-k dependent synthesis of biologically active forms of various clotting factors in addition to several regulatory factors.
Categories: 4-Hydroxycoumarins, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarinMidazolam
go.drugbank.com/drugs/DB00683ApprovedIllicitInvestigationalMidazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. … [A257153] Midazolam is considered a schedule IV drug in the United States due to the low potential for abuse and low risk of dependence.[L5074]
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: N/a, DORMICUM ® AMPOLLAS 5 MG/5 MLPentosan polysulfate
go.drugbank.com/drugs/DB00686ApprovedInvestigationalPentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Synonyms: (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULFATE, (4-O-METHYL-.ALPHA.-D-GLUCURONO)-(1->2)-(1->4)-.BETA.-D-XYLOPYRANAN, HYDROGEN SULPHATEProducts: MISURE ® GEL, MENTOSANIL®Flurazepam
go.drugbank.com/drugs/DB00690ApprovedIllicitA benzodiazepine derivative used mainly as a hypnotic.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesPhentolamine
go.drugbank.com/drugs/DB00692ApprovedInvestigationalPhentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation.
Categories: Peripheral alpha-1 blockers, Heterocyclic Compounds, 1-RingSynonyms: 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline, 3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOLMethazolamide
go.drugbank.com/drugs/DB00703ApprovedA carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.
Categories: Heterocyclic Compounds, 1-RingDelavirdine
go.drugbank.com/drugs/DB00705ApprovedInvestigationalWithdrawnA potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 InhibitorsSynonyms: (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide), 2-(4-(5-methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinaminePorfimer sodium
go.drugbank.com/drugs/DB00707ApprovedInvestigationalThe purified component of hematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds with 4 or More RingsLamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalIt is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.
Mixtures: N/A, N/ACategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingDiethylcarbamazine
go.drugbank.com/drugs/DB00711ApprovedInvestigationalVet approvedWithdrawnAn anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
Categories: Heterocyclic Compounds, 1-Ring