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GW 468816
go.drugbank.com/drugs/DB05417InvestigationalGW 468816 is glycine receptor antagonist. It is designed to aid abstinence in people who have just quit smoking, delaying the time to relapse. It was undergoing phase II trials since December 2003.
Categories: Receptors, N-Methyl-D-Aspartate, antagonists & inhibitors, Heterocyclic Compounds, 1-RingSR 140333
go.drugbank.com/drugs/DB05790ExperimentalSR 140333 is tachykinin antagonist which has potential to treat diarrhoea due to food allergy or inflammatory bowel disease.
Categories: Heterocyclic Compounds, 1-RingPyrimethamine
go.drugbank.com/drugs/DB00205ApprovedInvestigationalVet approvedOne of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsSynonyms: 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 2,4-Diamino-5-(P-chlorophenyl)-6-ethylpyrimidineSulfabenzamide
go.drugbank.com/drugs/DB09355ApprovedWithdrawnSulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.
Synonyms: N-Benzoylsulfanilamide, N-SulfanilylbenzamideAdrulipase alfa
go.drugbank.com/drugs/DB15004InvestigationalMS-1819 is under investigation in clinical trial NCT03481803 (A Phase IIa Study With Escalating Dose of MS1819-SD).
Synonyms: MS1819-SDGI heptapeptide
go.drugbank.com/drugs/DB15070InvestigationalGI heptapeptide is under investigation in clinical trial NCT01391208 (Esophageal Protocol for Detection of Neoplasia in the Digestive Tract).
Synonyms: GI heptapeptideOSI-7904L
go.drugbank.com/drugs/DB05457InvestigationalOSI-7904L is a liposome encapsulated thymidylate synthase inhibitor, which is indicated for use in advanced gastric and/or gastroesophageal adenocarcinoma (A-G/GEJA). … Current treatments also inhibit thymidylate synthase but the innovative lipid coating of OSI-7904L allows for more enduring results with administration of the TS inhibitor.
Categories: Heterocyclic Compounds, 2-RingPhensuximide
go.drugbank.com/drugs/DB00832ApprovedPhensuximide is a member of the succinimide class with anticonvulsant properties. … The frequency of attacks is reduced by depression of nerve transmission in the motor cortex.
Categories: Heterocyclic Compounds, 1-RingMethantheline
go.drugbank.com/drugs/DB00940ApprovedMethantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. … Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems