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Displaying results 5411 - 5420 of 10000 in total
  1. Drug

    Alvocidib

    go.drugbank.com/drugs/DB03496
    Investigational

    It works by inhibiting cyclin-dependent kinases, arresting cell division and causing apoptosis in non-small lung cancer cells. … Alvocidib is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer.

  2. Drug

    BZL101

    go.drugbank.com/drugs/DB05051
    Investigational

    BZL101 is an oral drug designed for the treatment of advanced breast cancer with a novel mechanism of action. BZL101 targets diseased cells while leaving normal cells healthy and intact.

  3. Indication

    Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 3

    go.drugbank.com/conditions/DBCOND0093776
    Drugs: Voxilaprevir
    Synonyms: Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 3
  4. Indication

    Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 4

    go.drugbank.com/conditions/DBCOND0093777
    Drugs: Voxilaprevir
    Synonyms: Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 4
  5. Indication

    Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 6

    go.drugbank.com/conditions/DBCOND0093779
    Drugs: Voxilaprevir
    Synonyms: Previously treated with an HCV regimen containing an NS5A inhibitor Chronic hepatitis C genotype 6
  6. Indication

    Autoimmune Hepatitis

    go.drugbank.com/conditions/DBCOND0032054
    Drugs: Mercaptopurine · Prednisone
    Synonyms: CAH - Chronic active hepatitis, CAH - Chronic aggressive hepatitis
  7. Drug

    Gataparsen

    go.drugbank.com/drugs/DB05141
    Investigational

    LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung, colon, breast, prostate, ovary, cervix, skin and brain. … LY2181308 is investigated in clinical trials for treating solid tumors. LY2181308 is a solid. LY2181308 is directed against a molecular target called survivin.

    Categories: Nucleic Acids, Nucleotides, and Nucleosides
  8. Drug

    LS11

    go.drugbank.com/drugs/DB05918
    Investigational

    After intratumoral activation by light emitting diodes, taporfin sodium forms an extended high energy conformational state that generates singlet oxygen, resulting in free radical-mediated cell death. … LS11(talaporfin sodium) is an agent consisting of chlorin e6, derived from chlorophyll, and L-aspartic acid with photosensitizing activity.

  9. Drug

    ORG-34517

    go.drugbank.com/drugs/DB05423
    Investigational

    It has potential to treat a number of diseases such as Cushing’s disease, hypertension, diabetes, glaucoma etc, in which the activity of metabolites corticosterone and cortisol is high. … ORG-34517 is currently under investigation by Organon for the treatment of depression.

  10. Drug

    1alpha,24S-Dihydroxyvitamin D2

    go.drugbank.com/drugs/DB06117
    Experimental

    It is developed for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD). Studies have shown LR-103 has the same potency as calcitriol, but much lower toxicity. … LR-103 is a naturally occurring D-hormone that is produced by the kidneys from vitamin D. LR-103 is one of the D-hormones produced from Hectorol.

    Categories: Vitamin D and Analogues