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Human Umbilical Cord Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15726InvestigationalThe cells are extracted by either the explant or the enzymatic digestion method, though neither method has been characterized as the ‘standard’ thus far. … The cord lining of the UC is generally isolated with the explant method -- resulting in two kinds of MSCs: cord lining mesenchymal stem cells (CLMC), which are used to aid in burn and diabetic ulcer wound
Horse chestnut
go.drugbank.com/drugs/DB13195InvestigationalHorse chestnut is a flowering plant commonly referred to as *Aesculus hippocastanum*. … The active component of this pure extract is escin, or aescin, that promotes blood circulation through the veins and reduces swelling and inflammation of the legs.
Mixtures: REPARİL-GEL N %1 + %5 JEL, 50 GProducts: FLEBOSTASIN R, Venostatin N Ointment 42mg/gmBupranolol
go.drugbank.com/drugs/DB08808ExperimentalBupranolol is a non-selective beta blocker with potency similar to [propanolol]. It does not have intrinsic sympathomimetic activity (ISA), but does have strong membrane stabilizing activity.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesIsoetharine
go.drugbank.com/drugs/DB00221ApprovedIsoetharine is a relatively selective beta-2 adrenergic agonist. It is a catechol-like agent. Isoetharine is a fast-acting bronchodilator used for emphysema, bronchitis and asthma.[A330]
Categories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsGMK
go.drugbank.com/drugs/DB06661ExperimentalGMK vaccine (a ganglioside conjugate vaccine coupled to keyhole limpet hemocyanin and formulated with the adjuvant QS-21) for the potential treatment of melanoma
Peginterferon alfacon-1
go.drugbank.com/drugs/DB05860ExperimentalPEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small … [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients with chronic hepatitis C infections.
Synonyms: PEG INF alfacon-1, Peginterferon alfacon-1Isoxsuprine
go.drugbank.com/drugs/DB08941ApprovedWithdrawnIts vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor. … A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.
Categories: 2-Amino-1-Phenylethanol DerivativesFormic acid
go.drugbank.com/drugs/DB01942ApprovedInvestigationalFormic acid (systematically called methanoic acid) is the simplest carboxylic acid. … It is an important intermediate in chemical synthesis and occurs naturally, most famously in the venom of bee and ant stings.
Mixtures: V-Natal, Irospan 24/6Lefradafiban
go.drugbank.com/drugs/DB04863InvestigationalLefradafiban is an oral platelet glycoprotein IIb/IIIa receptor antagonist being investigated in the treatment of angina.
Categories: Heterocyclic Compounds, 1-RingAmrubicin
go.drugbank.com/drugs/DB06263InvestigationalAmrubicin is a third-generation synthetic anthracycline currently in development for the treatment of small cell lung cancer. Pharmion licensed the rights to Amrubicin in November 2006. … Since January 2005, Amrubicin has been marketed by Nippon Kayaku, a Japanese pharmaceutical firm focused on oncology, which licensed Japanese marketing rights from Dainippon Sumitomo, the original developer