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SB-269970
go.drugbank.com/drugs/DB13988ExperimentalIn the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817] … SB-269970 is an experimental drug developed by GlaxoSmithKline.
Salts: SB-269970 hydrochlorideNSI-566
go.drugbank.com/drugs/DB17954InvestigationalNSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells. … Developed by Seneca Biopharma, it is being investigated for the treatment of amyotrophic lateral sclerosis (ALS), stroke, and chronic spinal cord injury (cSCI).[L47097]
Synonyms: NSI 566Salacetamide
go.drugbank.com/drugs/DB20217InvestigationalSalacetamide is a small molecule drug. … Salacetamide is under investigation in clinical trial NCT00220285 (Study for Evaluation of Efficacy and Safety of SH L 749 to Indolent B-cell Non-Hodgkin's Lymphoma).
Aftobetin
go.drugbank.com/drugs/DB20425InvestigationalAftobetin is a small molecule drug. … Aftobetin has a monoisotopic molecular weight of 452.23 Da.
Azilsartan mopivabil
go.drugbank.com/drugs/DB21569ExperimentalAzilsartan mopivabil is a small molecule drug. … The usage of the INN stem '-sartan' in the name indicates that Azilsartan mopivabil is a angiotensin II receptor antagonist, antihypertensive (non-peptidic).
Halazepam
go.drugbank.com/drugs/DB00801ApprovedIllicitWithdrawnHalazepam is a _benzodiazepine_ derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects. … [A1212] This drug is no longer marketed in the United States, and was withdrawn by _Schering_, its manufacturer, in 2009.[L6226, L6229]
Categories: Heterocyclic Compounds, 2-RingNilutamide
go.drugbank.com/drugs/DB00665ApprovedInvestigationalNilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). … Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer.
Synonyms: 5,5-Dimethyl-3-(α,α,α-trifluoro-4-nitro-m-tolyl)hydantoinCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnIt is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SEMIT(R) 10 MGCAPSULAS, SIBESY(R)10MG CAPSULASPentetrazol
go.drugbank.com/drugs/DB13415ApprovedWithdrawnPentetrazol, also known as pentylenetetrazole, is a gamma-aminobutyric acid type A (GABA<sub>A</sub>) receptor antagonist that was approved by the FDA until 1982.[A254437]
Categories: Heterocyclic Compounds, 1-Ring