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Displaying results 5441 - 5450 of 10000 in total
  1. Drug

    Alvespimycin

    go.drugbank.com/drugs/DB12442
    Investigational

    Alvespimycin is a derivative of geldanamycin and heat shock protein (HSP) 90 inhibitor. It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent.

  2. Drug

    IONIS-FGFR4Rx

    go.drugbank.com/drugs/DB16198
    Investigational

    IONIS-FGFR4Rx is under investigation in clinical trial NCT02476019 (A Safety, Tolerability, PK, and PD Study of Once Weekly ISIS-FGFR4RX SC in Obese Patients).

  3. Drug

    Ex vivo expanded autologous human corneal epithelial cells containing stem cells

    go.drugbank.com/drugs/DB18660
    ApprovedWithdrawn

    Holoclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.[L48375]

    Synonyms: Ex vivo expanded autologous human corneal epithelial cells containing stem cells
  4. Drug

    Gonyautoxin II

    go.drugbank.com/drugs/DB19186
    Investigational

    Gonyautoxin II is under investigation in clinical trial NCT04799041 (Gonyautoxin 2/3 in the Treatment of Acute Back Pain: A Clinical Proof-of-concept Study).

    Synonyms: 1h,10h-pyrrolo(1,2-c)purine-9,10,10-triol, 2,6-diamino-4-(((aminocarbonyl)oxy)methyl)-3a,4,8,9-tetrahydro-, 9-(hydrogen sulfate), (3as-(3a.alpha.,4.alpha.,9.beta.,10ar*))- 11.alpha., Gonyautoxin 2Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    BI-765063

    go.drugbank.com/drugs/DB17482
    Investigational

    BI-765063 is a humanized IgG4 monoclonal antibody antagonist of signal regulatory protein α (SIRPα).

  6. Drug

    Tribromsalan

    go.drugbank.com/drugs/DB20138
    ApprovedWithdrawn

    Tribromsalan is a small molecule drug. Tribromsalan has a monoisotopic molecular weight of 446.81 Da.

    Synonyms: 3,4',5-tribromosalicylanilide
  7. Drug

    MAS825

    go.drugbank.com/drugs/DB16452
    Investigational

  8. Drug

    Trypsin

    go.drugbank.com/drugs/DB11237
    ApprovedInvestigationalVet approved

    Trypsin is a serine protease that plays an essential role in protein hydrolysis and absorption in mammals. … Therapeutic forms of trypsin is obtained from purified extracts of porcine or bovine pancreas and is intended to aid in digestion when administered orally.

  9. Drug

    Black widow spider antivenin (equine)

    go.drugbank.com/drugs/DB14113
    Approved

    Black widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.[L12792]

    Synonyms: LATRODECTUS IMMUNE F(AB)2
  10. Drug

    Plutavimab

    go.drugbank.com/drugs/DB18856
    Investigational

    Plutavimab is under investigation in clinical trial NCT04900428 (Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)).

    Synonyms: Immunoglobulin g1 (234-alanine,235-alanine), anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding domain) (human monoclonal sti-2020 .gamma.1-chain), disulfide with, human monoclonal sti-2020 .kappa.