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Plazomicin
go.drugbank.com/drugs/DB12615ApprovedThe structure of plazomicin was established via appending hydroxylaminobutyric acid to [DB12604] at position 1 and 2-hydroxyethyl group at position 6' [A33942]. … It is marketed as Zemdri and is administered via once-daily intravenous infusion.
Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexCrobenetine
go.drugbank.com/drugs/DB21095InvestigationalCrobenetine has a monoisotopic molecular weight of 379.25 Da. … Crobenetine is a small molecule drug.
Dalzanemdor
go.drugbank.com/drugs/DB21549InvestigationalDalzanemdor has a monoisotopic molecular weight of 456.32 Da. … Dalzanemdor is a small molecule drug.
SYNB1891
go.drugbank.com/drugs/DB17541InvestigationalSYNB1891 is a live, modified strain of the probiotic _Escherichia coli_ Nissle engineered to produce cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway.
Nifurizone
go.drugbank.com/drugs/DB19694ExperimentalThe usage of the INN stem 'nifur-' in the name indicates that Nifurizone is a 5-nitrofuran derivative. Nifurizone has a monoisotopic molecular weight of 307.09 Da. … Nifurizone is a small molecule drug. The usage of the INN stem '-zone' in the name indicates that Nifurizone is a anti-inflammatory analgesic, phenylbutazone derivative.
Mequitazine
go.drugbank.com/drugs/DB01071InvestigationalMequitazine is a histamine H1 antagonist (antihistamine). … It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Onametostat
go.drugbank.com/drugs/DB21480InvestigationalOnametostat has a monoisotopic molecular weight of 482.11 Da. … Onametostat is a small molecule drug. The usage of the INN stem '-metostat' in the name indicates that Onametostat is a histone N-methyltransferase inhibitor.
Gamcemetinib
go.drugbank.com/drugs/DB21624InvestigationalGamcemetinib has a monoisotopic molecular weight of 469.1 Da. … Gamcemetinib is a small molecule drug. The usage of the INN stem '-tinib' in the name indicates that Gamcemetinib is a tyrosine kinase inhibitor.
Nifurethazone
go.drugbank.com/drugs/DB20112ExperimentalThe usage of the INN stem 'nifur-' in the name indicates that Nifurethazone is a 5-nitrofuran derivative. Nifurethazone has a monoisotopic molecular weight of 269.11 Da. … Nifurethazone is a small molecule drug. The usage of the INN stem '-azone' in the name indicates that Nifurethazone is a anti-inflammatory analgesic, phenylbutazone derivative.
Nadofaragene firadenovec
go.drugbank.com/drugs/DB17381ApprovedInvestigationalNadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). … [A255106,L44381] Nadofaragene firadenovec also has a manageable adverse event profile. Compared to [pembrolizumab], a smaller proportion of patients experienced grade 3-4 adverse events (4% vs 12.7%).