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Epofolate
go.drugbank.com/drugs/DB12266Investigationaland neutropenia appear to have been less frequent and less severe as compared to epothilones. … Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells.
Itepekimab
go.drugbank.com/drugs/DB16206InvestigationalItepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe
Lexacalcitol
go.drugbank.com/drugs/DB03451ExperimentalIt is known to target the vitamin D3 receptor. … This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane.
Cilomilast
go.drugbank.com/drugs/DB03849InvestigationalFollowing four clinical trials, the drug proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile.
Anivamersen
go.drugbank.com/drugs/DB16089InvestigationalAnivamersen is under investigation in clinical trial NCT01848106 (A Study to Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI).
Irsenontrine
go.drugbank.com/drugs/DB19044InvestigationalIrsenontrine is under investigation in clinical trial NCT03467152 (Study to Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia
Elezanumab
go.drugbank.com/drugs/DB15240InvestigationalElezanumab is under investigation in clinical trial NCT03737812 (A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis).
Afabicin
go.drugbank.com/drugs/DB15268InvestigationalAfabicin is under investigation in clinical trial NCT03723551 (Study to Assess Safety, Tolerability and Efficacy of Afabicin in The Treatment of Participants With Bone or Joint Infection Due to Staphylococcus
7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
go.drugbank.com/drugs/DB08550ExperimentalPotent reversible inhibitor of phenylethanolamine N-methyltransferase.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Phenylethanolamine N-Methyltransferase, antagonists & inhibitors