7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline

DB08550ExperimentalSmall molecule

Potent reversible inhibitor of phenylethanolamine N-methyltransferase.

Chemical structure of 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline
Formula / weight
C9H9Cl2N · 202.08 g/mol (avg)
Code names
SKF-64139 FREE BASE

Resolves to

Compound
UNIIA0EP5O913JCAS61563-24-4ChEMBLCHEMBL287837ChEBI160129PubChem123920
Structure
InChIKeyWFPUBEDBBOGGIQ-UHFFFAOYSA-NSMILESClC1=CC=C2CCNCC2=C1Cl
Targets
P08913ADRA2AP18825ADRA2CP18089ADRA2BP11086PNMT

What you can answer from here — as of January 29, 2025

4Protein targetsEach mapped to UniProt, with action and pharmacological action
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1,169Drug interactionsStructured to mechanism, not free text
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9+ReferencesStructured and connected to the statements they support
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Which drugs share a target with 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline, and which of those have an active Phase 3 trial?

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