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Displaying results 5441 - 5450 of 10000 in total
  1. Drug

    Mirfentanil

    go.drugbank.com/drugs/DB09175
    Experimental

    At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained … Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor.

  2. Drug

    CG7870

    go.drugbank.com/drugs/DB04981
    Investigational

    CG7870 is an oncolytic virus therapy for prostate cancer. … It is a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.

  3. Drug

    OT-551

    go.drugbank.com/drugs/DB05650
    Investigational

    It is intended to treat Age-related macular Degeneration (AMD), and preclinical research results indicate additional uses for OT-551, including treatment of early stage and advanced dry age-related macular … OT-551 is a novel small molecule that is topically dosed in an eye drop and has the unique ability to penetrate cell membranes and reach both the front and the back of the eye.

  4. Drug

    Sodium feredetate

    go.drugbank.com/drugs/DB13381
    Approved

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Black widow spider antivenin (equine)

    go.drugbank.com/drugs/DB14113
    Approved

    Black widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.[L12792]

  6. Drug

    Pegdinetanib

    go.drugbank.com/drugs/DB05931
    Investigational

    As a result, CT-322 blocks all known ligands for VEGFR-2. … CT-322 is a proprietary Adnectin(TM) protein therapeutic that, in preclinical studies, specifically binds to vascular endothelial growth factor receptor 2 (VEGFR-2), which regulates the primary tumor angiogenesis

  7. Drug

    Abdavomeran

    go.drugbank.com/drugs/DB15695
    Investigational

    [L15012] The modRNA is formulated in lipid nanoparticles for delivery via intramuscular injection. … BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.

    Categories: Experimental Unapproved Treatments for COVID-19
  8. Drug

    Tilarginine

    go.drugbank.com/drugs/DB11815
    ApprovedInvestigationalWithdrawn

    Tilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.

    Synonyms: N-Methylarginine, N(G)-Methylarginine
  9. Drug

    Laquinimod

    go.drugbank.com/drugs/DB06685
    Investigational

    It is currently under development in phase III trials for treatment of multiple sclerosis as an oral therapy, like fingolimod. … It has been shown to reduce disease activity on magnetic resonance imaging and to be well tolerated orally.

  10. Drug

    Thioredoxin

    go.drugbank.com/drugs/DB11298
    Approved

    Thioredoxin is a small dithiol protein and specific reductant for major allergenic proteins present in foods from animal and plant products. … It plays an essential role as an antioxidant in neutralizing food allergens and redox signalling. Allergens containing disulfide bonds are inactivated when reduced by thioredoxin.