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iCo-007
go.drugbank.com/drugs/DB05268InvestigationaliCo-007 (formerly known as ISIS 13650) is a second generation antisense compound being developed by iCo for the treatment of various eye diseases caused by the formation of new blood vessels (angiogenesis
Perenostobart
go.drugbank.com/drugs/DB18602InvestigationalPerenostobart is an alpha-CD39 IgG4 monoclonal antibody.
Vinylglycine
go.drugbank.com/drugs/DB03214ExperimentalVinylglycine is an irreversible inhibitor of aspartate aminotransferase.
Isopentane
go.drugbank.com/drugs/DB16203InvestigationalIsopentane is under investigation in clinical trial NCT00752089 (Experimental Dentifrice Remineralization/fluoride Uptake in an in Situ Model).
Tazarotene
go.drugbank.com/drugs/DB00799ApprovedIt is a prodrug that is found in topical formulations used in the treatment of various conditons, such as psoriasis, acne, and sun damaged skin (photodamage). … Tazarotene, commonly marketed as Tazorac®, Avage®, and Zorac®, is member of the acetylenic class of retinoids.
Cefmenoxime
go.drugbank.com/drugs/DB00267ApprovedCefmenoxime is a novel broad-spectrum and third-generation cephalosporin antibiotic that is typically used in the treatment of female gynecologic and obstetric infections. … It is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Carbonyl reductases (CBRs)
go.drugbank.com/bio_entities/BE0010129EnzymeHumansComponent of the heterotetramer complex KAR (3-ketoacyl-[acyl carrier protein] reductase or 3-ketoacyl-[ACP] reductase) that forms part of the mitochondrial fatty acid synthase (mtFAS). … Beta-subunit of the KAR heterotetramer complex, responsible for the 3-ketoacyl-ACP reductase activity of the mtFAS, reduces 3-oxoacyl-[ACP] to (3R)-hydroxyacyl-[ACP] in a NADPH-dependent manner with no
Synonyms: KAR beta subunitEtodolac
go.drugbank.com/drugs/DB00749ApprovedInvestigationalVet approvedIt is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. … Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties.
Aurodox
go.drugbank.com/drugs/DB04124ExperimentalAurodox is an antibiotic obtained from a streptomyces variant considered as possibly effective against streptococcus pyogenes infections. It may promote growth in poultry.