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DTx-1252
go.drugbank.com/drugs/DB18086ExperimentalDTx-1252 is a siRNA therapeutic under investigation for the treatment of Charcot-Marie-Tooth Disease type 1A (CMTD1A).[L48096]
PLG-0206
go.drugbank.com/drugs/DB18116InvestigationalPLG-0206 is a peptide antibiotic under investigation for the treatment of periprosthetic joint infections.[L48106]
PHE885
go.drugbank.com/drugs/DB18123InvestigationalPHE885 is an investigational, autologous B-cell Maturation Antigen (BCMA)-directed chimeric antigen receptor (CAR)-T cell therapy.
OTOF-GT
go.drugbank.com/drugs/DB18129InvestigationalOTOF-GT is a dual vector AAV gene therapy being investigated for the restoration of hearing loss associated with otoferlin deficiency.
PBKR03
go.drugbank.com/drugs/DB18138InvestigationalPBKR03 is a non-replicating recombinant adeno-associated virus serotype hu68 vector, containing a transgene encoding the human galactosylceramidase (GALC) enzyme.
TN-401
go.drugbank.com/drugs/DB18140InvestigationalTN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Synonyms: A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 geneBerbamine
go.drugbank.com/drugs/DB18146ExperimentalSynonyms: D-berbamine, 6,6',7-trimethoxy-2,2'-dimethylberbaman-12-olCategories: Heterocyclic Compounds, 2-RingCT103A
go.drugbank.com/drugs/DB18180InvestigationalCT103A is an investigational BCMA-targeted genetically modified autologous T-cell immunotherapy.
CT120
go.drugbank.com/drugs/DB18181InvestigationalCT120 is an investigational autologous CD19/22 targeted CAR-T cell immunotherapy.
Gunagratinib
go.drugbank.com/drugs/DB18191ExperimentalSynonyms: 1h-pyrazole-4-carboxamide, 3-(2-(3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1-((3s)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl)-, (s)-1-(1-acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1h-pyrazole-4-carboxamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates