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Displaying results 5461 - 5470 of 10000 in total
  1. Drug

    Drozitumab

    go.drugbank.com/drugs/DB19106
    Investigational

    It was developed by Genentech as a drug for the treatment of cancers … Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL)

    Synonyms: Immunoglobulin g1, anti-(human citokine receptor dr5 (death receptor 5)) (human monoclonal heavy chain), disulfide with human l3-chain, dimer
  2. Drug

    Linopristin

    go.drugbank.com/drugs/DB19296
    Experimental

    The combination product was under investigation in clinical trials NCT00653172 and NCT00949130 for treatment of various bacterial infections.

  3. Drug

    Narlaprevir

    go.drugbank.com/drugs/DB14760
    Investigational

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  4. Drug

    R-851

    go.drugbank.com/drugs/DB05747
    Experimental

    R-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate the human body's immnune system to attack virus-infected cells and tumor cells. … It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus (HPV), the sexually transmitted virus that causes most cases of cervical cancer.

  5. Drug

    Ramosetron

    go.drugbank.com/drugs/DB09290
    Investigational

    Currently, ramosetron is only approved for use Japan and in certain Southeast Asian countries. … Ramosetron is a _serotonin 5-HT3 receptor antagonist_ commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions.

  6. Drug

    GSK-923295

    go.drugbank.com/drugs/DB06097
    Investigational

    GSK-923295 demonstrated a broad spectrum of activity against a range of human tumor xenografts grown in nude mice, including models of colon, breast, ovarian, lung and other tumors. … GSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and the third novel drug candidate to arise from Cytokinetics' broad strategic alliance with GlaxoSmithKline

  7. Drug

    Efletirizine

    go.drugbank.com/drugs/DB20496
    Experimental

    Efletirizine is a small molecule drug. The usage of the INN stem '-rizine' in the name indicates that Efletirizine is a antihistaminic/cerebral (or peripheral) vasodilator. … Efletirizine has a monoisotopic molecular weight of 390.18 Da.

  8. Drug

    Benderizine

    go.drugbank.com/drugs/DB20870
    Experimental

    Benderizine is a small molecule drug. The usage of the INN stem '-rizine' in the name indicates that Benderizine is a antihistaminic/cerebral (or peripheral) vasodilator. … Benderizine has a monoisotopic molecular weight of 430.26 Da.

  9. Drug

    Maridebart Cafraglutide

    go.drugbank.com/drugs/DB19339
    Investigational

    , With or Without Type 2 Diabetes Mellitus). … Maridebart Cafraglutide is under investigation in clinical trial NCT05669599 (Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity

  10. Drug

    Bupranolol

    go.drugbank.com/drugs/DB08808
    Experimental

    Bupranolol is a non-selective beta blocker with potency similar to [propanolol]. It does not have intrinsic sympathomimetic activity (ISA), but does have strong membrane stabilizing activity.