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VPM1002
go.drugbank.com/drugs/DB15801InvestigationalVPM1002 is a recombinant BCG vaccine candidate expressing listeriolysin and deficient in urease that is generated in the genetic background of BCG Prague as it has a better safety profile than some other … As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
AAV1-FS344
go.drugbank.com/drugs/DB17855InvestigationalAAV1-FS344 is an investigational gene therapy developed by Milo Biotechnology to deliver follistatin, a potent myostatin inhibitor. … It is being investigated for the treatment of Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and inclusion body myositis.[L46742, L46747, L46752]
SRP-9005
go.drugbank.com/drugs/DB17958InvestigationalSRP-9005 is a rAAVrh74 vector containing a codon-optimized human SGCG transgene. … Developed by the Kurt+Peter Foundation and Sarepta Therapeutics, it is being investigated for the treatment of Limb-girdle muscular dystrophy (LGMD) type 2C/R5.[A260142]
Penamecillin
go.drugbank.com/drugs/DB13739ExperimentalCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSulglicotide
go.drugbank.com/drugs/DB13299ExperimentalCategories: Drugs for Acid Related Disorders, Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord)Terpin hydrate
go.drugbank.com/drugs/DB13163ApprovedWithdrawnTerpin hydrate is an expectorant, commonly used to loosen mucus and ease congestion in patients presenting with acute or chronic bronchitis, and related pulmonary conditions.
Mivebresib
go.drugbank.com/drugs/DB21300InvestigationalMivebresib has a monoisotopic molecular weight of 459.11 Da. … Mivebresib is under investigation in clinical trial NCT04480086 (Safety and Tolerability Study of Mivebresib Tablet Alone or in Combination With Ruxolitinib Tablet or Navitoclax Tablet in Adult Participants
SARS-CoV-2 Sclamp
go.drugbank.com/drugs/DB15849InvestigationalThe University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations (CEPI) and CSL has developed a COVID-19 candidate, SARS-CoV-2 Sclamp. … The vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine platform that locks surface proteins in a configuration that allows more robust immune responses, in combination with a well-established
Narlaprevir
go.drugbank.com/drugs/DB14760InvestigationalCategories: Antivirals for Systemic Use, Antiinfectives for Systemic UseR-851
go.drugbank.com/drugs/DB05747ExperimentalR-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate the human body's immnune system to attack virus-infected cells and tumor cells. … It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus (HPV), the sexually transmitted virus that causes most cases of cervical cancer.