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Displaying results 5471 - 5480 of 9333 in total
  1. Drug

    Mirfentanil

    go.drugbank.com/drugs/DB09175
    Experimental

    to discriminate morphine from naloxone. … Mirfentanil is a derivative of fentanyl that presents high selectivity for the mu opioid receptor.

  2. Drug

    Loprazolam

    go.drugbank.com/drugs/DB13643
    Experimental

    Loprazolam is recommended as a short-term therapy only, due to adverse events associated with the drug including dependence and withdrawal symptoms. … It is a positive modulator of GABA-A receptor that enhances the inhibitory neurotransmission. It is not an FDA-approved drug.

  3. Drug

    AS1409

    go.drugbank.com/drugs/DB05182
    Investigational

    One is the cytokine IL12, which has anti-cancer activity. The other is an antibody that targets tumours. … It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and melanoma.

  4. Drug

    Egg phospholipids

    go.drugbank.com/drugs/DB14233
    ApprovedWithdrawn

    Egg phospholipids are primarily a mixture of naturally occurring phospholipids which are isolated from the egg yolk.

  5. Drug

    Thiram

    go.drugbank.com/drugs/DB13245
    Approved

    Thiram may be used in dermatology as a scabicide [T436].

  6. Drug

    Iron isomaltoside 1000

    go.drugbank.com/drugs/DB12208
    ApprovedInvestigationalWithdrawn

    Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney Disease, and Anemia, Iron-Deficiency, among others.

  7. Drug

    TAK-428

    go.drugbank.com/drugs/DB05499
    Experimental

    It is based on the novel concept that peripheral nervous tissue that was damaged by diabetes can be repaired and regenerated by stimulating an increase in neurotrophic factors.

  8. Drug

    Pralnacasan

    go.drugbank.com/drugs/DB04875
    Experimental

    Pralnacasan is an orally bioavailable pro-drug of a potent, non-peptide inhibitor of interleukin-1beta converting enzyme (ICE).

  9. Drug

    Virus Specific T-Cell

    go.drugbank.com/drugs/DB15735
    Investigational

    These T-cells are then isolated from the donor and expanded in a culture to generate more VSTs. … Antigens identified as an immune target are presented by antigen-presenting cells (APCs) to T-cells along with other molecules that stimulate their growth and activation.

    Synonyms: Viral Specific T-lymphocytes, HLA-matched Virus Specific T Cells
  10. Drug

    Tetrathiomolybdate

    go.drugbank.com/drugs/DB05088
    Investigational

    It is also developed for fibrotic disorders based upon the rationale that the fibrotic disease process is dependent upon the availability of free copper in the body. … COPREXA has completed pivotal clinical trials for the treatment of neurologic Wilson's disease.