Search

Displaying results 5471 - 5480 of 8697 in total
  1. Drug

    Afimetoran

    go.drugbank.com/drugs/DB16580
    Investigational

    Afimetoran is an immunomodulator and an antagonist of toll-like receptors 7 and 8.

  2. Drug

    Sulopenem etzadroxil

    go.drugbank.com/drugs/DB16335
    ApprovedInvestigational

    [L51768] Sulopenem etzadroxil was approved by the FDA in October 2024 for the treatment of uncomplicated urinary tract infections.

  3. Drug

    HNM01

    go.drugbank.com/drugs/DB06531
    Experimental

    It entered Phase 1 clinical trials for the treatment of HIV infections but was discontinued during this phase … The drug hNM01, a humanized monoclonal antibody developed by SRD Pharmaceuticals, Inc., targets the V(3) region of the HIV-1 envelope protein gp120, functioning as an HIV replication inhibitor.

  4. Drug

    VPM4001

    go.drugbank.com/drugs/DB05089
    Experimental

    VPM4001 is an allogeneic vaccine for treatment of prostate carcinoma.

  5. Target

    Intercellular adhesion molecule 1

    go.drugbank.com/bio_entities/BE0001085
    TargetHumans

    Also functions as a ligand receptor of the signaling receptor ITGAM:ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed:1980124). … Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing

    Synonyms: Major group rhinovirus receptor
  6. Drug

    CYP-001

    go.drugbank.com/drugs/DB15739
    Investigational

    The MCA-derived MSCs can be obtained from induced pluripotent stem cells (iPSCs) and then expanded in media. … These cells have advantage over other MSCs because a large amount can be obtained from a single healthy blood donor, negating the risks from donor-and expansion dependent variability.

  7. Drug

    SAB-185

    go.drugbank.com/drugs/DB16491
    Investigational

    Categories: Experimental Unapproved Treatments for COVID-19
  8. Drug

    RPI-MN

    go.drugbank.com/drugs/DB17957
    Experimental

    RPI-MN is a detoxified or chemically modified alpha-cobratoxin with antiviral properties. … [A260132] Being developed by Nutra Pharma under the trade name PEPTERON, it is being investigated for the treatment of neurological and immune disorders.[L47107]

    Synonyms: RPI-MN
  9. Drug

    Emodepside

    go.drugbank.com/drugs/DB11403
    InvestigationalVet approved

    Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats and belongs to the class of drugs known as the octadepsipeptides, a relatively

  10. Target

    CD27 antigen

    go.drugbank.com/bio_entities/BE0010071
    TargetHumans

    Costimulatory immune-checkpoint receptor expressed at the surface of T-cells, NK-cells and B-cells which binds to and is activated by its ligand CD70/CD27L expressed by B-cells (PubMed:28011863).

    Synonyms: CD27L receptor, Tumor necrosis factor receptor superfamily member 7