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Nafarelin
go.drugbank.com/drugs/DB00666ApprovedInvestigationalNafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central precocious puberty and endometriosis.
(S)-Propafenone
go.drugbank.com/drugs/DB15410Investigational(S)-Propafenone is under investigation in clinical trial NCT02710669 (New Formulations of Propafenone to Treat Atrial Fibrillation).
ETBX-011
go.drugbank.com/drugs/DB17464InvestigationalETBX-011 is a cancer vaccine used to treat patients with cancers that express carcinoembryonic antigen (CEA).
TUM012
go.drugbank.com/drugs/DB18652InvestigationalTUM012 is a synthetic polymer PEG conjugated to a phospholipid anchor (2-dipalmitoyl-sn-glycerol-3-phosphatidylethanolamine)
(R)-Propafenone
go.drugbank.com/drugs/DB19162InvestigationalPropafenone, (r)- is under investigation in clinical trial NCT02710669 (New Formulations of Propafenone to Treat Atrial Fibrillation).
Azelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigational[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996.
Asoprisnil
go.drugbank.com/drugs/DB06680InvestigationalIt can be used to treat progesterone sensitive myomata.
RAG-17
go.drugbank.com/drugs/DB18503InvestigationalRAG-17 is a siRNA oligonucleotide designed to target and knockdown the expression of superoxide dismutase (SOD).
Aminoflavone
go.drugbank.com/drugs/DB19077InvestigationalAminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).
LJP 1082
go.drugbank.com/drugs/DB05446ExperimentalLJP 1082 is a Toleragen that is designed to shut down the B cells that produce antibodies to ß2 GP1. … To date, our scientists have shown that approximately 90% of patients studied with antibody-mediated thrombosis have antibodies that bind to this region.