(R)-Propafenone

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
(R)-Propafenone
DrugBank Accession Number
DB19162
Background

Propafenone, (r)- is under investigation in clinical trial NCT02710669 (New Formulations of Propafenone to Treat Atrial Fibrillation).

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 341.451
Monoisotopic: 341.199093733
Chemical Formula
C21H27NO3
Synonyms
  • (+)-(r)-propafenone
  • (+)-propafenone
  • (R)-propafenone
  • 1-propanone, 1-(2-((2r)-2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
X44T90MGR0
CAS number
107381-31-7
InChI Key
JWHAUXFOSRPERK-GOSISDBHSA-N
InChI
InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3/t18-/m1/s1
IUPAC Name
SMILES
CCCNC[C@@H](O)COC1=CC=CC=C1C(=O)CCC1=CC=CC=C1

References

General References
Not Available
ChemSpider
160686
ChEMBL
CHEMBL1788268
ZINC
ZINC000001530760
PDBe Ligand
4Y4
PDB Entries
7fbs

Clinical Trials

Clinical Trials
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PhaseStatusPurposeConditionsCountStart DateWhy Stopped100+ additional columns
1, 2TerminatedTreatmentAtrial Fibrillation1somestatusstop reasonjust information to hide

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at July 05, 2024 18:37 / Updated at July 06, 2024 06:45