(R)-Propafenone

DB19162InvestigationalSmall molecule

Propafenone, (r)- is under investigation in clinical trial NCT02710669 (New Formulations of Propafenone to Treat Atrial Fibrillation).

Chemical structure of (R)-Propafenone
Mechanism
Curator reviewed
Formula / weight
C21H27NO3 · 341.451 g/mol (avg)
Also known as
(+)-(r)-propafenone · (+)-propafenone · 1-propanone, 1-(2-((2r)-2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-

Resolves to

Compound
UNIIX44T90MGR0CAS107381-31-7ChEMBLCHEMBL1788268
Structure
InChIKeyJWHAUXFOSRPERK-GOSISDBHSA-NSMILESCCCNC[C@@H](O)COC1=CC=CC=C1C(=O)CCC1=CC=CC=C1
Targets
Q92736RYR2

What you can answer from here — as of July 09, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with (R)-Propafenone, and which of those have an active Phase 3 trial?

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