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Displaying results 5481 - 5490 of 10000 in total
  1. Drug

    Siltuximab

    go.drugbank.com/drugs/DB09036
    ApprovedInvestigational

    It is administered as a 1 hour intravenous infusion every 3 weeks. … Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology.

  2. Drug

    Fasinumab

    go.drugbank.com/drugs/DB12157
    Investigational

    Fasinumab is a human IgG1k monoclonal antibody targeted against nerve growth factor (NGF). … [A241190] It has since been recognized for its role in nociceptive signaling transduction and has thus become an attractive target in the treatment of chronic pain conditions.

  3. Drug

    Ad5-nCoV

    go.drugbank.com/drugs/DB15655
    Investigational

    )[L12675] with an expected completion in December 2020. … Ad5-nCoV is a recombinant adenovirus type-5 vector (Ad5) vaccine currently being investigated for prophylaxis against SARS-CoV-2.

  4. Drug

    Mephenytoin

    go.drugbank.com/drugs/DB00532
    ApprovedWithdrawn

    Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. … Mephenytoin is a hydantoin-derivative anticonvulsant used to control various partial seizures.

  5. Drug

    PB127

    go.drugbank.com/drugs/DB06208
    Investigational

  6. Drug

    Magnesium aspartate

    go.drugbank.com/drugs/DB13359
    Investigational

    Magnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement. … It displays high oral bioavailability and water solubiltiy compared to other magnesium salts such as magnesium citrate, magnesium carbonate and magnesium oxide.

  7. Drug

    MC-1

    go.drugbank.com/drugs/DB05315
    Experimental

    Medicure's MC-1 drug is a cardio-protectant, designed to reduce the damage to the heart when arteries are blocked and when they are subsequently reopened after bypass surgery.

  8. Drug

    HLX-58

    go.drugbank.com/drugs/DB18699
    Experimental

    HLX-58 is an investigational monoclonal antibody targeted against claudin 18.2.

  9. Drug

    Apc001

    go.drugbank.com/drugs/DB17819
    Experimental

    Apc001 is an aptamer developed for the treatment of osteogenesis imperfecta.

  10. Drug

    BA1301

    go.drugbank.com/drugs/DB19390
    Investigational

    BA1301 is an anti-Claudin18.2 monoclonal antibody conjugated with Duostatin-5.