Search
Fingolimod
go.drugbank.com/drugs/DB08868ApprovedInvestigational[A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. … [L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with the SARS-CoV-2 virus.[L12654,L12657]
Categories: Experimental Unapproved Treatments for COVID-19, P-glycoprotein inducersProducts: Mar-fingolimodOxidronic acid
go.drugbank.com/drugs/DB14159ApprovedSynonyms: HMD-PProducts: TECHNESCAN HDP FOR INJECTION 3 mg/vial, TECHNESCAN HDP POWDER FOR INJECTION 3.15 mg/vialSemaglutide
go.drugbank.com/drugs/DB13928ApprovedInvestigationalSemaglutide offers a competitive advantage over other drugs used to manage diabetes, which may require several daily doses. … [L41335] On May 31, 2023, the FDA issued a warning regarding the use of compounded semaglutide after receiving adverse event reports.
Products: OZEMPIC 1MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML, OZEMPIC 0.25MG, 0.5MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/MLSildenafil
go.drugbank.com/drugs/DB00203ApprovedInvestigationalNevertheless, it is because of this mechanism that sildenafil is also indicated for treating pulmonary arterial hypertension but is also additionally notorious for interacting with various anti-anginal … Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common and effective treatment for erectile dysfunction and since its formal approval for medical use in
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: BRIOS KOMPLET MAN, Mar-sildenafilRomosozumab
go.drugbank.com/drugs/DB11866ApprovedInvestigationalIn a comparison study of post menopausal women with osteoporosis and a past fracture, romosozumab for 12 months followed by alendronic acid for 12 months was superior to alendronic acid alone for 24 months … Romosozumab prevents bone resorption and induces the formation of bone though it is associated with an increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924].
Categories: Drugs for Treatment of Bone DiseasesProducts: EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 ML, EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17MLTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigational[A182300] Similar to other opioid medications, tramadol poses a risk for development of tolerance, dependence and abuse. … Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain.
Mixtures: Mar-tramadol/acet, NODOL MAX® TABLETA RECUBIERTACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAxicabtagene ciloleucel
go.drugbank.com/drugs/DB13915ApprovedInvestigationalAxicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. … can produce cytokines that efficiently kill leukemic cells _in vitro_.
Categories: CD19 Receptor Interactions, CD19-directed Chimeric Antigen ReceptorSynonyms: Autologous T cells transduced with retroviral vector encoding an anti-CD-19 CD28/CD3-zeta chimeric antigen receptorCefuroxime
go.drugbank.com/drugs/DB01112ApprovedInvestigationalIt has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Cefuroxime Axetil For Oral Suspension, Hovid Cmaxid for Injection 1.5gInsulin detemir
go.drugbank.com/drugs/DB01307ApprovedInvestigational[A2358, A2359, A2360, A44] Insulin also inhibits hepatic glucose production, enhances protein synthesis, and inhibits lipolysis and proteolysis among many other functions. … [A2358, A2359, A2360, A44] The absorption of glucose into cells allows for its transformation into glycogen or fat for storage.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Levemir FlexPen 100U/ML Solution for injection in a prefilled pen, Levemir® FlexPen® 100 U/ml Solution for Injection in Pre-filled PenVinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalVinflunine ditartrate is an active ingredient in the EMA-authorised product Javlor for intravenous infusion. … In murine tumors and human tumor xenografts, vinflunine exhibits an antitumor efficacy than [DB00361], [DB00570], and [DB00541] [A31975].
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: Javlor Concentrate for Solution for Infusion 25 mg/mL