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NCX 950
go.drugbank.com/drugs/DB05849ExperimentalNCX 950, beta2-adrenoceptor agonists is widely used in the treatment of pulmonary diseases.
IL-2 pDNA
go.drugbank.com/drugs/DB05935ExperimentalVical incorporated has initiated a human Phase 1 study of an investigational method of delivering interleukin-2 (IL-2), a potent immune system stimulant, for patients with recurrent metastatic melanoma
ABT-560
go.drugbank.com/drugs/DB06093ExperimentalABT-560 is a neuronal nicotinic receptor (NNR) modulator, which has shown promise in preclinical models relevant for the treatment of cognitive deficits.
Sphingosine
go.drugbank.com/drugs/DB03203InvestigationalAn amino alcohol with a long unsaturated hydrocarbon chain. Sphingosine and its derivative sphinganine are the major bases of the sphingolipids in mammals. (Dorland, 28th ed)
NUC B1000
go.drugbank.com/drugs/DB05242ExperimentalOn January 11, 2008, it was announced that NUC B1000 was entering a phase 1 human safety study of its experimental treatment for chronic Hepatitis B virus (HBV) infection. … NUC B1000 is an expressed interfering RNA (eiRNA)- based product consisting of a plasmid DNA construct designed to produce four short interfering RNA (siRNA) molecules, formulated with a proprietary cationic-lipid
UCB7362
go.drugbank.com/drugs/DB17096Experimentalin mice) studies. … [A254232] UCB7362 is estimated to achieve a significant reduction in asexual blood-stage parasites.
beta-Hydroxybutyric acid
go.drugbank.com/drugs/DB16506InvestigationalBeta-hydroxybutyrate is being studied in around 230 clinical trials, including NCT06351124 (recruiting for Crohn's disease), NCT05584371 (recruiting for safety and tolerability of exogenous ketosis), NCT04656236
Apolizumab
go.drugbank.com/drugs/DB06467InvestigationalApolizumab is a humanized monoclonal antibody that is being studied as a treatment for hematologic cancers.
GS-441524
go.drugbank.com/drugs/DB15686InvestigationalGS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir].[A203057,L13239] This molecule was patented in 2009. … [L13775] _In vitro_ studies of GS-441524 have determined it has a higher EC<sub>50</sub> than remdesivir against a number of viruses, meaning GS-441524 is less potent.