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Nordazepam
go.drugbank.com/drugs/DB14028InvestigationalIt may have actions similar to those of diazepam.
Trotabresib
go.drugbank.com/drugs/DB17421InvestigationalTrotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal (BET) proteins.
Synonyms: Bet inhibitor cc-90010Agerafenib
go.drugbank.com/drugs/DB15068InvestigationalAgerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).
EC-0652
go.drugbank.com/drugs/DB15340ExperimentalEC-0652 is under investigation in clinical trial NCT02202447 (Phase 1 of EC1169 In Patients With Recurrent MCRPC).
Adipiplon
go.drugbank.com/drugs/DB06579InvestigationalIt is known by the standardized identifier NG2-73.
Sparsomycin
go.drugbank.com/drugs/DB04222ExperimentalIt inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
Ezatiostat
go.drugbank.com/drugs/DB05460InvestigationalIt might also be relevant as an adjunct therapy since a reduction in blood cell levels is also a common, toxic effect of many standard chemotherapeutic drugs. … It acts intracellularly on the MAPK signaling pathway by activating ERK2.
20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)
go.drugbank.com/bio_entities/BE0009795EnzymeHumans and other mammalsCytosolic aldo-keto reductase that catalyzes NADPH-dependent reduction of ketosteroids to hydroxysteroids. Displays broad substrate specificity with distinct positional and stereochemistry, primarily generating 20alpha-hydroxysteroids, b...
Synonyms: CHDRPifusertib
go.drugbank.com/drugs/DB15054InvestigationalTAS-117 is under investigation in clinical trial NCT03017521 (K-BASKET, TAS-117, PI3K/AKT Gene Aberration).
Tiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigational[A180163] Tiotropium was granted FDA approval on 30 January 2004.[L7084]