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Pelitinib
go.drugbank.com/drugs/DB05524InvestigationalPelitinib (EKB-569) is a potent, low molecular weight, selective, and irreversible inhibitor of epidermal growth factor receptor (EGFR) that is being developed as an anticancer agent.
Synonyms: (2E)-N-(4-((3-chloro-4-fluorophenyl)amino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-2-butenamideSaredutant
go.drugbank.com/drugs/DB06660InvestigationalSaredutant (SR 48968) is a neurokinin-2 antagonist drug being developed as an antidepressant and anxiolytic by Sanofi-Aventis.
Roquinimex
go.drugbank.com/drugs/DB11366ExperimentalRoquinimex is a derivative of quinoline that presents immunostimulant properties. Its effects are suggested to increase the activity of NK cells and macrophage cytotoxicity. … Additionally, roquinimex is known to inhibit angiogenesis and to decrease the synthesis of TNF alpha.
BZL101
go.drugbank.com/drugs/DB05051InvestigationalBZL101 is an oral drug designed for the treatment of advanced breast cancer with a novel mechanism of action. BZL101 targets diseased cells while leaving normal cells healthy and intact.
Pargyline
go.drugbank.com/drugs/DB01626ApprovedPargyline is a monoamine oxidase inhibitor with antihypertensive properties.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesPantethine
go.drugbank.com/drugs/DB11190ApprovedIt consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. … Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine.
Synonyms: D-Bis(N-pantothenyl-beta-aminoethyl) disulfideCinchophen
go.drugbank.com/drugs/DB13551ExperimentalCategories: Preparations With No Effect on Uric Acid MetabolismEthacizine
go.drugbank.com/drugs/DB13645ExperimentalCategories: Antiarrhythmics, Class I, Antiarrhythmics, Class IcMesmulogene ancovacivec
go.drugbank.com/drugs/DB06584Investigationalresulting in tumor cell lysis. … A bivalent cancer vaccine comprised of a modified vaccinia virus Ankara (MVA) strain encoding human mucin 1 (MUC1) and interleukin-2 (IL-2) with potential immunostimulating and antineoplastic activities
Inolimomab
go.drugbank.com/drugs/DB15628InvestigationalIt has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.[A241385] … Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease.