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DB11190ApprovedSmall molecule
Pantethine is a naturally occurring compound derived from panthothenic acid. It acts as an intermediate in endogenous coenzyme A synthesis and is used as a dietary supplement to treat hypertriglyceridemia. It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A.
- Mechanism
- Curator reviewed
Pharmacologically active on Ubiquitin C-terminal hydrolase PSMD14
- Formula / weight
- C22H42N4O8S2 · 554.721 g/mol (avg)
- Also known as
- D-pantethine · Pantomin
Resolves to
Clinical / RWD
Structure
InChIKey
DJWYOLJPSHDSAL-ROUUACIJSA-NSMILESCC(C)(CO)[C@@H](O)C(=O)NCCC(=O)NCCSSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COTargets
What you can answer from here — as of July 06, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
Which drugs share a target with Pantethine, and which of those have an active Phase 3 trial?