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Clesrovimab
go.drugbank.com/drugs/DB18877Approvedpatients, nor are vaccines immediately effective in this population, clesrovimab and similar monoclonal antibodies like [nirsevimab] are designed to provide passive immunization against RSV infection as an
MGD-024
go.drugbank.com/drugs/DB17265InvestigationalMGD-024 is an anti-CD123/anti-CD3 bispecific DART molecule.
MEDI-547
go.drugbank.com/drugs/DB18360InvestigationalMEDI-547 is an anti-EphA1 monoclonal antibody conjugated to mcMMAF
2G7
go.drugbank.com/drugs/DB18589Experimental2G7 is an anti-TGF-beta monoclonal antibody developed by Genentech.
Norvaline
go.drugbank.com/drugs/DB04185InvestigationalNorvaline is an isomer of the more common amino acid valine.
Lebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigationalLebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate. It binds to a different epitope compared tralokinumab. On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYS...
Avanafil
go.drugbank.com/drugs/DB06237ApprovedAvanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but l...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesCarprofen
go.drugbank.com/drugs/DB00821ApprovedVet approvedWithdrawnCarprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years...
Pilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigationalA naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist. Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Inhibitors(S)-camphor
go.drugbank.com/drugs/DB11345ApprovedIt has been used as a nasal decongestant and cough suppressant, and has been topically applied due to its antipruritic, analgesic, and counterirritant properties [A33086].
Mixtures: U Ice Cold, U Ice Cold