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Displaying results 5531 - 5540 of 7181 in total
  1. Drug

    Londamocitinib

    go.drugbank.com/drugs/DB19190
    Investigational

    Londamocitinib is under investigation in clinical trial NCT06020014 (Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-severe Asthma Uncontrolled on Medium-high

    Synonyms: (R)-N-(3-(5-Fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)pyrimidin-4-yl)-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide, 1-piperazineacetamide, n-(3-(5-fluoro-2-((2-fluoro-3-(methylsulfonyl)phenyl)amino)-4-pyrimidinyl)-1h-indol-7-yl)-.alpha.-(methoxymethyl)-4-methyl-, (.alpha.r)-
  2. Drug

    COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection

    go.drugbank.com/drugs/DB15845
    Experimental

    The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity. … As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’

    Synonyms: AP-TP-V, COVID-19 AP TP Vaccine
  3. Drug

    ABT-072

    go.drugbank.com/drugs/DB15156
    Investigational

    ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat

  4. Drug

    R-851

    go.drugbank.com/drugs/DB05747
    Experimental

    R-851 is part of the family of immune response modifier (IRM) and it acts in a novel way to stimulate the human body's immnune system to attack virus-infected cells and tumor cells. … It is expected to be topical treatment for cervical displasia and cervical high-risk human papillomavirus (HPV), the sexually transmitted virus that causes most cases of cervical cancer.

  5. Drug

    S-Hydroxycysteine

    go.drugbank.com/drugs/DB01915
    Experimental

    This compound belongs to the alpha amino acids and derivatives. … These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.

  6. Drug

    GTI 2040

    go.drugbank.com/drugs/DB05801
    Investigational

    It belongs to the family of drugs called antisense oligonucleotides.

  7. Drug

    St. John's Wort

    go.drugbank.com/drugs/DB01323
    ApprovedInvestigationalNutraceutical

    Synonyms: Klamathweed flowering top, Common st johnswort flowering topCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  8. Drug

    Friulimicin B

    go.drugbank.com/drugs/DB06087
    Investigational

    Friulimicin B is a naturally occurring antibiotic produced by a micro-organism, *Actinoplanes friuliensis*.

  9. Drug

    Maplirpacept

    go.drugbank.com/drugs/DB18441
    Investigational

    Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.

  10. Drug

    Nortriptyline

    go.drugbank.com/drugs/DB00540
    ApprovedInvestigational

    Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.

    Synonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamineCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome