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Displaying results 5531 - 5540 of 10000 in total
  1. Drug

    Solithromycin

    go.drugbank.com/drugs/DB09308
    Investigational

    Solithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  2. Drug

    Altropane I-123

    go.drugbank.com/drugs/DB15144
    Investigational

    Altropane I-123 is under investigation in clinical trial NCT01950468 (A Cross-Over, Multi-Center Trial to Evaluate the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the

    Synonyms: Altropane I-123
  3. Drug

    Aluminum zirconium pentachlorohydrate

    go.drugbank.com/drugs/DB11147
    Approved

    Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body. … Aluminum zirconium pentachlorohydrate is a common active ingredient in personal care products as an antiperspirant agent.

    Products: Skin So Soft Original Anti-Perspirant Deodorant, Skin So Soft Soft and Sensual Anti-Perspirant Deodorant
  4. Drug

    Methylone

    go.drugbank.com/drugs/DB19192
    Investigational

    Methylone is under investigation in clinical trial NCT05741710 (A Study to Assess the use of Methylone in the Treatment of PTSD).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 1-propanone, 1-(1,3-benzodioxol-5-yl)-2-(methylamino)-, 3,4-methylenedioxy-n-methylcathinone
  5. Drug

    ISIS 14803

    go.drugbank.com/drugs/DB05803
    Investigational

    ISIS 14803 is a 20-unit antisense phosphorothioate oligodeoxynucleotide that binds to hepatitis C virus (HCV) RNA at the translation initiation region of the internal ribosome entry site (IRES) and inhibits

  6. Drug

    Indium In-111 pentetate

    go.drugbank.com/drugs/DB09425
    ApprovedInvestigational

    Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. … Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography.

  7. Drug

    SGN-15

    go.drugbank.com/drugs/DB05818
    Investigational

    SGN-15 is studied in the treatment of cancer. It combines a monoclonal antibody with the anticancer drug doxorubicin. … Monoclonal antibodies are substances that are made in the laboratory and that can locate and bind to cancer cells. Doxorubicin is a type of anthracycline antitumor antibiotic.

  8. Drug

    CRx-139

    go.drugbank.com/drugs/DB05744
    Experimental

    It is a dissociated steroid designed to enhance the immuno-modulatory activity of a low-dose glucocorticoid steroid without a comparable increase in steroid-related side effects. … This novel synergistic combination is developed for the treatment of immuno-inflammatory diseases.

  9. Drug

    Vatalanib

    go.drugbank.com/drugs/DB04879
    Investigational

    Vatalanib is under investigation for the treatment of solid tumors. … Vatalanib (PTK787/ZK-222584) is a new oral antiangiogenic molecule that inhibits all known vascular endothelial growth factor receptors.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    PBI-1402

    go.drugbank.com/drugs/DB05480
    Experimental

    The compound activates neutrophils, enhancing their survival and activation with comparable efficacy to GM-CSF, G-CSF and EPO, which are currently used to treat anemia. … PBI-1402 appears to work on the PMN pathway, but its specific binding properties are not known. PBI-1402 has a dual therapeutic action; as a chemoprotectant and hematopoietic progenitor stimulator.