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Esmirtazapine
go.drugbank.com/drugs/DB06678InvestigationalEsmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. … Merck has terminated its internal clinical development program for esmirtazapine as of March 2010.
Synonyms: (S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepineAER001
go.drugbank.com/drugs/DB05078InvestigationalAER001, an IL4/13 receptor antagonist for severe asthma and eczema currently in Phase 2 studies.
SPP1148
go.drugbank.com/drugs/DB05203ExperimentalSPP1148, the most promising compound from a new series of renin inhibitors for the treatment of hypertension and related end-organ disease.
Enokizumab
go.drugbank.com/drugs/DB05555InvestigationalA humanized immunoglobulin G1k anti-interleukin-9 mAb.
Verpasep caltespen
go.drugbank.com/drugs/DB04959InvestigationalIt is being developed by StressGen Biotechnologies Corp. … E7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes.
VSF-173
go.drugbank.com/drugs/DB05753InvestigationalVSF-173 is an oral small molecule. It is an oral compound that has demonstrated effects on animal sleep/wake patterns and gene expression patterns suggestive of a stimulant effect. … It is developed for the treatment of excessive sleepiness. Study shows that VSF-173 possesses a novel mechanism to address disorders of excessive sleepiness.
OC-1012
go.drugbank.com/drugs/DB05834ExperimentalOC-1012 is a compound which has emerged as a promising therapeutic agent for the treatment and prevention of mucositis, a serious side effect of chemotherapy and head and neck radiation therapy.