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TG-1042
go.drugbank.com/drugs/DB18435InvestigationalTG-1042 (formerly known as ASN-002) is a recombinant adenovirus carrying the cDNA coding sequence for the human interferon gamma gene.
R411
go.drugbank.com/drugs/DB05468ExperimentalR411 is a non-steroid oral medicine for the treatment of asthma. It is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation. … It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to either a4b1 or a4b7.
(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide
go.drugbank.com/drugs/DB06941ExperimentalThis compound belongs to the phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group. This drug targets the protein S100B.
4-(4-fluoro-phenylazo)-5-imino-5H-pyrazol-3-ylamine
go.drugbank.com/drugs/DB08667ExperimentalThis compound belongs to the fluorobenzenes. These are compounds containing one or more fluorine atoms attached to a benzene ring. This substance targets the protein methionine aminopeptidase.
Clocapramine
go.drugbank.com/drugs/DB09003ExperimentalIn addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic. … Clocapramine is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 for the treatment of schizophrenia.
GTI 2040
go.drugbank.com/drugs/DB05801InvestigationalIt belongs to the family of drugs called antisense oligonucleotides.
Alisertib
go.drugbank.com/drugs/DB05220InvestigationalAlisertib is a novel aurora A kinase inhibitor under investigation for the treatment of various forms of cancer.
G207
go.drugbank.com/drugs/DB05827InvestigationalThese viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores. … G207 is cancer-killing viruses, so-called oncolytic viruses, for the treatment of various forms of cancer developed by MediGene AG.
SO-101
go.drugbank.com/drugs/DB05345ExperimentalDoxepin has been prescribed for more than 40 years for the treatment of depression and anxiety at dosages typically ranging from 75 mg to 300 mg per day.
Altretamine
go.drugbank.com/drugs/DB00488ApprovedWithdrawnAn alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.