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Displaying results 5541 - 5550 of 8412 in total
  1. Drug

    Lebrikizumab

    go.drugbank.com/drugs/DB11914
    ApprovedInvestigational

    Lebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate. It binds to a different epitope compared tralokinumab. On November 17, 2023, lebrikizumab was approved by the EMA under the brand name EBGLYS...

  2. Drug

    Avanafil

    go.drugbank.com/drugs/DB06237
    Approved

    Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but l...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  3. Drug

    Carprofen

    go.drugbank.com/drugs/DB00821
    ApprovedVet approvedWithdrawn

    Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. Carprofen was previously used in human medicine for over 10 years...

  4. Drug

    Pilocarpine

    go.drugbank.com/drugs/DB01085
    ApprovedInvestigational

    A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist. Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine ...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Inhibitors
  5. Drug

    Glycerol phenylbutyrate

    go.drugbank.com/drugs/DB08909
    ApprovedInvestigational

    Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP2D6 Inhibitors
  6. Drug

    Phenothiazine

    go.drugbank.com/drugs/DB11447
    ExperimentalVet approved

    Phenothiazine (PTZ) is an organic thiazine compound.

  7. Drug

    Aluminium acetoacetate

    go.drugbank.com/drugs/DB13280
    Experimental

    Aluminium acetoacetate is an aluminum containing antacid.

  8. Drug

    Rimazolium

    go.drugbank.com/drugs/DB13289
    Experimental

    Rimazolium is an experimental analgesic drug [A176186].

  9. Drug

    Diphenyleneiodonium

    go.drugbank.com/drugs/DB17025
    Experimental

    An NADPH oxidase 2 (NOX2) inhibitor.[A252987]

  10. Drug

    Acecainide

    go.drugbank.com/drugs/DB17602
    Experimental

    Acecainide is an investigational anti-arrhythmia drug.