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Displaying results 5541 - 5550 of 7604 in total
  1. Drug

    IDM-2

    go.drugbank.com/drugs/DB05293
    Experimental

    IDM-2 is composed of Monocyte-derived Activated Killer (MAK) cells. IDM produces MAK cells from the patient's own white blood cells by activating these cells ex vivo to allow them to recognize and destroy tumor cells.

  2. Drug

    Dirlotapide

    go.drugbank.com/drugs/DB11399
    InvestigationalVet approved

    It is marketed by Pfizer and Zoetis under the brand name, _Slentrol_, and is not intended for human use.

  3. Drug

    tgAAVCF

    go.drugbank.com/drugs/DB17849
    Investigational

    It is being investigated for the treatment of cystic fibrosis.[A259821, A259826]

  4. Drug

    Tubercidin

    go.drugbank.com/drugs/DB03172
    Experimental

    An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids

  5. Target

    Endoplasmic reticulum membrane sensor NFE2L1

    go.drugbank.com/bio_entities/BE0004168
    TargetHumans

    In response to stress, it is released from the endoplasmic reticulum membrane following cleavage by the protease DDI2 and translocates into the nucleus to form the transcription factor NRF1 (By similarity … Acts as a key sensor of cholesterol excess: in excess cholesterol conditions, the endoplasmic reticulum membrane form of the protein directly binds cholesterol via its CRAC motif, preventing cleavage and

    Synonyms: Protein NRF1, p120 form
  6. Drug

    Flomoxef

    go.drugbank.com/drugs/DB11935
    Investigational

    Flomoxef has been used in trials studying the treatment of Urinary Tract Infection.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  7. Drug

    Levonadifloxacin

    go.drugbank.com/drugs/DB16219
    Investigational

    Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)).

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  8. Drug

    Cannabidivarin

    go.drugbank.com/drugs/DB14050
    Investigational

    In October 2017 CBDV was given orphan designation by the European Medicines Agency for use in Rett Syndrome [L2952] and again in February 2018 for treatment of Fragile X Syndrome [L2951]. … Unfortunately, as of February 2018, GW Pharmaceuticals announced that their Phase 2a placebo-controlled study of CBDV for focal seizure did not reach its primary endpoints.

  9. Drug

    Furazidin

    go.drugbank.com/drugs/DB13475
    Experimental

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use
  10. Drug

    Betamipron

    go.drugbank.com/drugs/DB19858
    Experimental

    Betamipron is a small molecule drug. Betamipron has a monoisotopic molecular weight of 193.07 Da.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic Use