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Displaying results 5551 - 5560 of 10000 in total
  1. Drug

    Pipequaline

    go.drugbank.com/drugs/DB13991
    Experimental

    Pipequaline has a similar pharmacological profile to the reported for the benzodiazepines. … It presents a unique chemical structure that does not follow the structural properties of other drugs of its class.

  2. Drug

    Lexibulin

    go.drugbank.com/drugs/DB05147
    Investigational

    CYT997 is an orally available vascular targeting and cytotoxic agent that has proven effective in animal models of a wide range of tumour types including breast, prostate and colon, as well as some leukemias

  3. Target

    Prolyl tripeptidyl peptidase

    go.drugbank.com/bio_entities/BE0004097
    TargetPorphyromonas gingivalis (strain ATCC BAA-308 / W83)

    Has a requirement for Pro in the P1 position, but is inactivated by Pro in the P1' position.

    Synonyms: Prolyl tripeptidyl peptidase 81.8 kDa form
  4. Drug

    Arylacenamide

    go.drugbank.com/drugs/DB05792
    Experimental

    Arylacenamide (SR31747) is a peripheral [sigma] ligand that binds four proteins in human cells, i.e. SRBP-1, [sigma]-2, HSI and its relative SRBP-2. … It is a dual agent with both immunomodulatory and antiproliferative activities.

  5. Drug

    MEM 1003

    go.drugbank.com/drugs/DB05547
    Investigational

    MEM 10003 was under investigation in clinical trial NCT00257673 (Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease) for the treatment of Alzheimer's Disease

  6. Drug

    LG-100268

    go.drugbank.com/drugs/DB01941
    Experimental

    LG-100268 is a retinoid X receptor (RXR) selective compound.

  7. Drug

    ADL 10-0101

    go.drugbank.com/drugs/DB05443
    Experimental

    Because ADL 10-0101 does not cross the blood-brain barrier and enter the brain when administered at therapeutic doses, it is expected to avoid central nervous system side effects. … Preclinical trials of ADL 10-0101 have suggested that the compound may be effective for the treatment of inflammatory pain, itch and visceral pain.

  8. Drug

    Washed Microbiota Transplantation

    go.drugbank.com/drugs/DB15745
    Investigational

    The resulting suspension is shown to decrease FMT-related adverse events. … Fecal microbiota transplantation (FMT) is effective in enhancing the gut microbiota of patients experiencing a high range of disease states, including Clostridioides difficile (C. diff) infection, Crohn

  9. Drug

    Contulakin-G

    go.drugbank.com/drugs/DB05950
    Experimental

    Contulakin-G is a broad spectrum non-opioid analgesic. It is the synthetic form of a natural peptide extracted from the venom of the Conus Geographus sea snail.

  10. Drug

    Lonaprisan

    go.drugbank.com/drugs/DB16221
    Investigational

    Lonaprisan is under investigation in clinical trial NCT00555919 (ZK 230211 in Postmenopausal Woman With Metastatic Breast Cancer).