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Equilin
go.drugbank.com/drugs/DB02187ExperimentalAn estrogenic steroid produced by horses. It has a total of four double bonds in the A- and B-ring. High concentration of equilin is found in the urine of pregnant mares.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDitiocarb
go.drugbank.com/drugs/DB02520InvestigationalA chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.
Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A InhibitorsPeldesine
go.drugbank.com/drugs/DB02568InvestigationalPeldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
Categories: N-Glycosyl Hydrolases, antagonists & inhibitors, Cytochrome P-450 SubstratesN-Ethylretinamide
go.drugbank.com/drugs/DB03917ExperimentalN-Ethylretinamide is the ethylamide of all-trans B-retinoic acid.
Synonyms: all-trans-N-EthylretinamideN-acetyl-beta-neuraminic acid
go.drugbank.com/drugs/DB04265ExperimentalAn N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Synonyms: N-acetyl-β-neuraminic acid, N-acetyl-beta-neuraminic acidEstrone sulfate
go.drugbank.com/drugs/DB04574ApprovedEstrone sulfate (as estropipate) is a form of estrogen. It has several uses such as: alleviate symptoms of menopause as hormone replacement therapy, treatment some types of infertility, treatment of some conditions leading to underdevelo...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsIproniazid
go.drugbank.com/drugs/DB04818ApprovedWithdrawnWithdrawn from the Canadian market in July 1964 due to interactions with food products containing tyrosine.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 CYP2D6 InhibitorsLysergic acid diethylamide
go.drugbank.com/drugs/DB04829IllicitInvestigationalDebate continues over the nature and causes of chronic flashbacks. Explanations in terms of LSD physically remaining in the body for months or years after consumption have been discounted by experimental evidence. Some say HPPD is a mani...
Synonyms: N,N-diethyllysergamide, N,N-diethyl-D-lysergamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTienilic acid
go.drugbank.com/drugs/DB04831ApprovedWithdrawnTienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension. It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen an...
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsMethaqualone
go.drugbank.com/drugs/DB04833ApprovedIllicitWithdrawnMethaqualone is a sedative-hypnotic drug that is similar in effect to barbiturates, a general central nervous system depressant. The sedative-hypnotic activity was first noted by Indian researchers in the 1950s and in 1962 methaqualone i...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates