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Aphidicolin
go.drugbank.com/drugs/DB17742ExperimentalIt inhibits DNA polymerase alpha and blocks DNA replication.[A259157, A259162]
Synonyms: 8,11a-methano-11ah-cyclohepta(a)naphthalene-4,9-dimethanol, tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-, (3r,4r,4ar,6as,8r,9r,11as,11bs)-TRK-001
go.drugbank.com/drugs/DB18577InvestigationalTRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Synonyms: Natural Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and Transforming Growth Factor-betaElismetrep
go.drugbank.com/drugs/DB15287InvestigationalElismetrep is under investigation in clinical trial NCT02429102 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of MT-8554 in Healthy Subjects).
Dextromoramide
go.drugbank.com/drugs/DB01529ExperimentalIllicit(From Martindale, The Extra Pharmacopoeia, 30th ed, p1070)
EMZ702
go.drugbank.com/drugs/DB05021InvestigationalEMZ702 has an excellent safety profile and the combination of EMZ702 with interferon and ribavirin in surrogate models for hepatitis C has demonstrated a two to three fold increase in anti-viral potency … EMZ702, a non-toxic agent that has strong anti-viral synergy with interferon, is an ideal candidate for combination with current standard hepatitis C treatments.
Cyclomethicone 5
go.drugbank.com/drugs/DB11244ApprovedCyclomethicone 5 is used in cosmetic and personal products as a skin emollient.
Anisodamine
go.drugbank.com/drugs/DB11785InvestigationalAnisodamine has been investigated for the treatment of Intestinal Diseases.
Serlopitant
go.drugbank.com/drugs/DB12973InvestigationalSerlopitant has been investigated for the treatment of Prurigo Nodularis.
Orteronel
go.drugbank.com/drugs/DB12066InvestigationalOrteronel has been investigated for the treatment of Prostate Cancer.