Cyclomethicone 5

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Cyclomethicone 5
Accession Number
DB11244
Description

Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient.

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 370.77
Monoisotopic: 370.093956741
Chemical Formula
C10H30O5Si5
Synonyms
  • Ciclopentasiloxane
  • Cyclomethicone D5
  • Cyclopentasiloxane
  • Decamethylcyclopentasiloxane
External IDs
  • KF 995
  • KF-995
  • SF 1202
  • VS 7158

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
Learn More
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Learn about our commercial Adverse Effects data.
Learn More
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

Purchasing individual compounds or compound libraries for your research?
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Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
3ce CR Eamy Water Proof Eye Liner 01 CatsLiquid0.16 g/0.6gTopicalNanda Co., Ltd2016-08-102018-12-01US flag
3ce CR Eamy Water Proof Eye Liner 02 ZorroLiquid0.18 g/0.6gTopicalNanda Co., Ltd2016-08-102018-12-01US flag
3ce CR Eamy Water Proof Eye Liner 08 Les MiserablesLiquid0.18 g/0.6gTopicalNanda Co., Ltd2016-08-102018-12-01US flag
3ce CR Eamy Water Proof Eye Liner 13 CaffeineLiquid0.20 g/0.6gTopicalNanda Co., Ltd2016-08-102018-12-01US flag
3ce Pink Im Good MascaraLiquid0.17 g/8.5gTopicalNanda Co., Ltd.2016-08-01Not applicableUS flag
BpCream3.6 g/30mLTopicalMiguhara2016-01-02Not applicableUS flag
Lightening SerumCream0.35 mg/20mgTopicalLange SAS2012-07-18Not applicableUS flag
Mefactory Super Clear Lip And Eye RemoverLiquid80.0 g/200mLTopicalMeFactory Co., Ltd.2017-12-012018-10-01US flag
Additional Data Available
  • Application Number
    Application Number
    Available for Purchase

    A unique ID assigned by the FDA when a product is submitted for approval by the labeller.

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  • Product Code
    Product Code
    Available for Purchase

    A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Secret Key Tattoo Cover Cushion Spf50 Plus (21 Light Beige)Cyclomethicone 5 (8 g/100g) + Octinoxate (7 g/100g) + Phenyl trimethicone (3.5 g/100g) + Propylene glycol (5 g/100g) + Titanium dioxide (12 g/100g)LiquidTopicalZenpia2016-09-272018-12-19US flag
Secret Key Tattoo Cover Cushion Spf50 Plus (23 Natural Beige)Cyclomethicone 5 (8 g/100g) + Octinoxate (7 g/100g) + Phenyl trimethicone (3.5 g/100g) + Propylene glycol (5 g/100g) + Titanium dioxide (12 g/100g)LiquidTopicalZenpia2016-09-272018-12-19US flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
3ce CR Eamy Water Proof Eye Liner 01 CatsCyclomethicone 5 (0.16 g/0.6g)LiquidTopicalNanda Co., Ltd2016-08-102018-12-01US flag
3ce CR Eamy Water Proof Eye Liner 02 ZorroCyclomethicone 5 (0.18 g/0.6g)LiquidTopicalNanda Co., Ltd2016-08-102018-12-01US flag
3ce CR Eamy Water Proof Eye Liner 08 Les MiserablesCyclomethicone 5 (0.18 g/0.6g)LiquidTopicalNanda Co., Ltd2016-08-102018-12-01US flag
3ce CR Eamy Water Proof Eye Liner 13 CaffeineCyclomethicone 5 (0.20 g/0.6g)LiquidTopicalNanda Co., Ltd2016-08-102018-12-01US flag
3ce Pink Im Good MascaraCyclomethicone 5 (0.17 g/8.5g)LiquidTopicalNanda Co., Ltd.2016-08-01Not applicableUS flag
BpCyclomethicone 5 (3.6 g/30mL)CreamTopicalMiguhara2016-01-02Not applicableUS flag
Lightening SerumCyclomethicone 5 (0.35 mg/20mg)CreamTopicalLange SAS2012-07-18Not applicableUS flag
Mefactory Super Clear Lip And Eye RemoverCyclomethicone 5 (80.0 g/200mL)LiquidTopicalMeFactory Co., Ltd.2017-12-012018-10-01US flag
Secret Key Tattoo Cover Cushion Spf50 Plus (21 Light Beige)Cyclomethicone 5 (8 g/100g) + Octinoxate (7 g/100g) + Phenyl trimethicone (3.5 g/100g) + Propylene glycol (5 g/100g) + Titanium dioxide (12 g/100g)LiquidTopicalZenpia2016-09-272018-12-19US flag
Secret Key Tattoo Cover Cushion Spf50 Plus (23 Natural Beige)Cyclomethicone 5 (8 g/100g) + Octinoxate (7 g/100g) + Phenyl trimethicone (3.5 g/100g) + Propylene glycol (5 g/100g) + Titanium dioxide (12 g/100g)LiquidTopicalZenpia2016-09-272018-12-19US flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as organoheterosilanes. These are organosilicon compounds where the tetravalent silicon atom is linked to one or more heteroatoms.
Kingdom
Organic compounds
Super Class
Organometallic compounds
Class
Organometalloid compounds
Sub Class
Organosilicon compounds
Direct Parent
Organoheterosilanes
Alternative Parents
Organic metalloid salts / Organic oxygen compounds / Hydrocarbon derivatives
Substituents
Aliphatic heteromonocyclic compound / Hydrocarbon derivative / Organic metalloid salt / Organic oxygen compound / Organic salt / Organoheterosilane
Molecular Framework
Aliphatic heteromonocyclic compounds
External Descriptors
Not Available

Chemical Identifiers

UNII
0THT5PCI0R
CAS number
541-02-6
InChI Key
XMSXQFUHVRWGNA-UHFFFAOYSA-N
InChI
InChI=1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3
IUPAC Name
decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
SMILES
C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1

References

General References
Not Available
PubChem Compound
10913
PubChem Substance
347827949
ChemSpider
10451
RxNav
1305744
ChEMBL
CHEMBL1885178
ZINC
ZINC000169743678

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
LiquidTopical0.16 g/0.6g
LiquidTopical0.18 g/0.6g
LiquidTopical0.20 g/0.6g
LiquidTopical0.17 g/8.5g
CreamTopical3.6 g/30mL
CreamTopical0.35 mg/20mg
LiquidTopical80.0 g/200mL
LiquidTopical
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00803 mg/mLALOGPS
logP4.08ALOGPS
logP0.96ChemAxon
logS-4.7ALOGPS
pKa (Strongest Basic)-3.3ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count5ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area46.15 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity66.21 m3·mol-1ChemAxon
Polarizability35.09 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created on December 03, 2015 09:51 / Updated on June 12, 2020 10:53

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