Cyclomethicone 5
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This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- Cyclomethicone 5
- DrugBank Accession Number
- DB11244
- Background
Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
- Weight
- Average: 370.77
Monoisotopic: 370.093956741 - Chemical Formula
- C10H30O5Si5
- Synonyms
- Ciclopentasiloxane
- Cyclomethicone D5
- Cyclopentasiloxane
- Decamethylcyclopentasiloxane
- External IDs
- KF 995
- KF-995
- SF 1202
- VS 7158
Pharmacology
- Indication
Not Available
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
- Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.
- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image 3ce CR Eamy Water Proof Eye Liner 01 Cats Liquid 0.16 g/0.6g Topical Nanda Co., Ltd. 2016-08-10 2018-12-01 US 3ce CR Eamy Water Proof Eye Liner 02 Zorro Liquid 0.18 g/0.6g Topical Nanda Co., Ltd. 2016-08-10 2018-12-01 US 3ce CR Eamy Water Proof Eye Liner 08 Les Miserables Liquid 0.18 g/0.6g Topical Nanda Co., Ltd. 2016-08-10 2018-12-01 US 3ce CR Eamy Water Proof Eye Liner 13 Caffeine Liquid 0.20 g/0.6g Topical Nanda Co., Ltd. 2016-08-10 2018-12-01 US 3ce Pink Im Good Mascara Liquid 0.17 g/8.5g Topical Nanda Co., Ltd. 2016-08-01 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Liquid Cyclomethicone 5 (25 mg/100mg) + Butane (30 mg/100mg) + Glycerin (25 mg/100mg) Spray Cutaneous Shantou Youjia E-Commerce Co., Ltd. 2024-02-01 2024-12-31 US Secret Key Tattoo Cover Cushion Spf50 Plus (21 Light Beige) Cyclomethicone 5 (8 g/100g) + Octinoxate (7 g/100g) + Phenyl trimethicone (3.5 g/100g) + Propylene glycol (5 g/100g) + Titanium dioxide (12 g/100g) Liquid Topical Zenpia 2016-09-27 2018-12-19 US Secret Key Tattoo Cover Cushion Spf50 Plus (23 Natural Beige) Cyclomethicone 5 (8 g/100g) + Octinoxate (7 g/100g) + Phenyl trimethicone (3.5 g/100g) + Propylene glycol (5 g/100g) + Titanium dioxide (12 g/100g) Liquid Topical Zenpia 2016-09-27 2018-12-19 US - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image 3ce CR Eamy Water Proof Eye Liner 01 Cats Cyclomethicone 5 (0.16 g/0.6g) Liquid Topical Nanda Co., Ltd. 2016-08-10 2018-12-01 US 3ce CR Eamy Water Proof Eye Liner 02 Zorro Cyclomethicone 5 (0.18 g/0.6g) Liquid Topical Nanda Co., Ltd. 2016-08-10 2018-12-01 US 3ce CR Eamy Water Proof Eye Liner 08 Les Miserables Cyclomethicone 5 (0.18 g/0.6g) Liquid Topical Nanda Co., Ltd. 2016-08-10 2018-12-01 US 3ce CR Eamy Water Proof Eye Liner 13 Caffeine Cyclomethicone 5 (0.20 g/0.6g) Liquid Topical Nanda Co., Ltd. 2016-08-10 2018-12-01 US 3ce Pink Im Good Mascara Cyclomethicone 5 (0.17 g/8.5g) Liquid Topical Nanda Co., Ltd. 2016-08-01 Not applicable US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as organoheterosilanes. These are organosilicon compounds where the tetravalent silicon atom is linked to one or more heteroatoms.
- Kingdom
- Organic compounds
- Super Class
- Organometallic compounds
- Class
- Organometalloid compounds
- Sub Class
- Organosilicon compounds
- Direct Parent
- Organoheterosilanes
- Alternative Parents
- Organic metalloid salts / Organic oxygen compounds / Hydrocarbon derivatives
- Substituents
- Aliphatic heteromonocyclic compound / Hydrocarbon derivative / Organic metalloid salt / Organic oxygen compound / Organic salt / Organoheterosilane
- Molecular Framework
- Aliphatic heteromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 0THT5PCI0R
- CAS number
- 541-02-6
- InChI Key
- XMSXQFUHVRWGNA-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3
- IUPAC Name
- decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
- SMILES
- C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1
References
- General References
- Not Available
- External Links
- PubChem Compound
- 10913
- PubChem Substance
- 347827949
- ChemSpider
- 10451
- 1305744
- ChEMBL
- CHEMBL1885178
- ZINC
- ZINC000169743678
Clinical Trials
- Clinical Trials
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Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Liquid Topical 0.16 g/0.6g Liquid Topical 0.18 g/0.6g Liquid Topical 0.20 g/0.6g Liquid Topical 0.17 g/8.5g Cream Topical 3.6 g/30mL Cream Topical 0.35 mg/20mg Spray Cutaneous Liquid Topical 80.0 g/200mL Liquid Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.00803 mg/mL ALOGPS logP 4.08 ALOGPS logP 0.96 Chemaxon logS -4.7 ALOGPS pKa (Strongest Basic) -3.3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 46.15 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 66.21 m3·mol-1 Chemaxon Polarizability 35.09 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M+H]+ 157.0689263 predictedDarkChem Lite v0.1.0 [M+Na]+ 156.7213263 predictedDarkChem Lite v0.1.0
Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53