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Isoxicam
go.drugbank.com/drugs/DB08942ApprovedWithdrawnIsoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingThallium Tl-201
go.drugbank.com/drugs/DB15361InvestigationalThallium Tl-201 is under investigation in clinical trial NCT02697760 (The CZT Dynamic Myocardial Perfusion Imaging).
Synonyms: Thallium Tl-201Mebeverine
go.drugbank.com/drugs/DB12554ApprovedInvestigationalWithdrawnMebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.
Products: DUSPATALIN® CÁPSULA DE LIBERACIÓN PROLONGADA 200 MG, DUSPATALIN CÁPSULA DE LIBERACIÓN PROLONGADA 200 MG.Clorindione
go.drugbank.com/drugs/DB13275ExperimentalClorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans.
Categories: Vitamin K AntagonistsDYN-101
go.drugbank.com/drugs/DB17921InvestigationalDYN-101 is an antisense product candidate designed to reduce the expression of dynamin 2 protein.
Synonyms: 5’-cEtG-sp-cEt5MeU-sp-cEt5MeU-sp-dT-sp-dA-sp-dT-sp-dT-spdA-sp-dT-sp-dA-sp-dG-sp-dG-sp-dG-sp-cEt5MeC-sp-cEt5MeU-sp-cEt5MeU-3’Asimadoline
go.drugbank.com/drugs/DB05104InvestigationalIt has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases. … Asimadoline is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis.
Categories: Heterocyclic Compounds, 1-RingInhibitor of P38 Kinase
go.drugbank.com/drugs/DB01953ExperimentalInhibitor of P38 Kinase is a solid. This compound belongs to the indoles. These are compounds containing an indole moiety, which consists of a pyrrole ring fused to benzene to form 2,3-benzopyrrole. … This drug is known to target mitogen-activated protein kinase 14.
Solithromycin
go.drugbank.com/drugs/DB09308InvestigationalSolithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesPYM50018
go.drugbank.com/drugs/DB05126ExperimentalWhen administered orally to a transgenic pre-clinical model of ALS, PYM50018 delays the loss of muscle strength and extends survival time. … PYM50018 is a patented, orally active, neuroprotective and neuroregenerative compound. It is developed for the treatment of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).
GEM-231
go.drugbank.com/drugs/DB05798InvestigationalGEM231 is a second-generation antisense oligonucleotide targeting the mRNA of the R1alpha regulatory subunit of cAMP dependent protein kinase. … A monoclonal antibody combined with a toxic substance that is used treat certain types of acute myeloid leukemia in older patients and is being studied in the treatment of other types of cancer.