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Nadifloxacin
go.drugbank.com/drugs/DB12447InvestigationalNadifloxacin has been used in trials studying the treatment of Acne Vulgaris.
Categories: Anti-Acne Preparations for Topical Use, Antiinfectives for Treatment of AcneFlutrimazole
go.drugbank.com/drugs/DB13425InvestigationalFlutrimazole is a topical imidazole antifungal agent with broad spectrum activity.[A275033]
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseThiocolchicoside
go.drugbank.com/drugs/DB11582InvestigationalThiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of _Superba gloriosa_. … It is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663]
TM30339
go.drugbank.com/drugs/DB05085ExperimentalTM30339 thus imitates a natural mechanism, a satiety signal from the gastrointestinal system involved in the regulation of food intake in humans. TM30339 is developed for the treatment of obesity.
NTx-265
go.drugbank.com/drugs/DB05649InvestigationalIt is also investigating use of the compound for neurodegenerative disorders, such as Huntington’s disease and Alzheimer’s disease. … NTx-265 is a combination of two currently marketed large molecules designed to stimulate the growth and differentiation of neural stem cells in adults who have suffered a stroke – the second leading cause
Taragarestrant
go.drugbank.com/drugs/DB21574InvestigationalTaragarestrant is under investigation in clinical trial NCT06954961 (A Study to Evaluate D-0502 in Subjects With ER+ Her2- Locally Advanced or Metastatic Breast Cancer). … Taragarestrant has a monoisotopic molecular weight of 474.13 Da.
OSI-461
go.drugbank.com/drugs/DB05415InvestigationalOSI-461 is a second-generation molecule belonging to a new class of drugs termed selective apoptotic anti-neoplastic drugs (SAANDs).
Pozanicline
go.drugbank.com/drugs/DB05458InvestigationalABT-089 is a neuronal nicotinic acetylcholine receptor agonist that may have therapeutic utility for the treatment of several neurological disorders including Alzheimer, Attention Deficit Hyperactivity
ARG098
go.drugbank.com/drugs/DB06338ExperimentalARG098 (anti-Fas IgM monoclonal antibody) was studied in a Phase I clinical trial in 2007 involving patients with rheumatoid arthritis.
Danaparoid
go.drugbank.com/drugs/DB06754ApprovedWithdrawnDanaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans [A32565]. … Danaparoid possesses a potent antithrombic activity that works by inhibiting activated factor X (Factor Xa) and activated factor II (Factor IIa).